Molecular Mechanisms Related to Exercise
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 2
Special Issue Editor
Special Issue Information
Dear Colleagues,
Regular exercise induces long-term systemic adaptations with positive effects on the musculoskeletal, respiratory, cardiovascular, and nervous systems as well as on metabolism and redox balance. These changes are mediated by molecular and intracellular mechanisms, including the regulation of gene expression and the activation of signaling pathways that primarily account for mitochondrial biogenesis, increased glucose uptake, angiogenesis, muscle hypertrophy, bone formation, the release of neurotrophic factors, and molecules with antioxidant capabilities and anti-inflammatory effects.
Therefore, this Special Issue aims to provide a platform for original research and review articles to understand the physiological, molecular, and intracellular mechanisms associated with physical activity, which are the foundation of the primary adaptations induced by regular exercise.
Dr. Giorgia Scarfò
Guest Editor
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Keywords
- exercise
- mitochondrial biogenesis
- intracellular pathways
- inflammation
- oxidative stress
- hypertrophy
- metabolism angiogenesis
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