Molecular Mechanisms of Neurological and Psychiatric Disease, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 November 2025
Special Issue Editors
2. Department of Human Sciences, Faculty of Humanities Educations and Sports, Pegaso University, 80143 Naples, Italy
Interests: pathophysiology; movement disorders; motor memory; motor dysfunction; synaptic plasticity; brain circuitry; basal ganglia; striatum (putamen); medium spiny neurons; mitochondria; neurologic and phychiatric disorders; protein synthesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Until several decades ago, psychological and behavioural interventions were the primary treatments for mental health disorders.
Thanks to modern psychopharmacology, medications are accepted to treat more psychiatric disorders.
Unfortunately, the mechanism behind many medications is unknown. Several therapeutic approaches are derived from neurological pathologies.
Psychiatric disorders are often present in various neurological diseases like Alzheimer's and Parkinson's disease, epilepsy, migraine, essential tremors, and stroke. Depression, anxiety disorders, and cognitive impairment are the most common comorbid diagnoses in neurological diseases. It is important to note that comorbidities are frequently overlooked due to common neurochemical mechanisms or a loss of previous functioning levels.
Moreover, some medications may have drawbacks, including drug interactions, side effects, and low effectiveness. In light of these, evidence has become essential to characterize the molecular mechanism of neurological and psychiatric disease to ensure the best treatments are utilized.
The colossal effort of researchers to increase the knowledge of many psychiatric and neurological disorders in the last few decades has helped us to understand not only the developmental stages of many diseases but, principally, the mechanism of action of medication on specific molecular targets.
This Special Issue aims to collect original research articles (regular and rapid communication) and reviews on the underlying molecular mechanisms of psychiatric and degenerative diseases and the therapeutic properties of substances, including those derived from plants.
Dr. Giuseppina Martella
Dr. Maria Meringolo
Guest Editors
Manuscript Submission Information
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Keywords
- Alzheimer's and Parkinson's diseases
- epilepsy
- migraine
- essential tremors
- stroke
- depression
- anxiety disorders
- cognitive impairment
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