Bioactive Compound Delivery Systems and Microbiome Interactions
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 1309
Special Issue Editors
Interests: nutrigenomics; metagenomics; metaproteomics; metabolomics; metatranscriptomics; understanding the molecular mechanisms of food compounds; molecular nutrition; personalised nutrition; personalised food; medical foods; aging and chronic disease; aging and NCDs; climate/environment, health, and improved nutrition; diet and cancer; dietary bioactive components; prebiotics fiber; nutrient-gene interactions; nutritional epidemiology; nutritional immunology and inflammation; obesity and microbiome; gut-brain axis; nutritional microbiology
Special Issues, Collections and Topics in MDPI journals
Interests: oxidative stress; antioxidant polyphenols; anti-inflammatory; antimicrobial polyphenols; bioactive compound; biological activities
Special Issues, Collections and Topics in MDPI journals
Interests: polyphenols; bioavailability; bio-accessibility; bioactivity; antioxidant; biotechnological; chemical treatment
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bioactive compounds and nutraceuticals have grown significantly in recent years, and extensive research has been conducted on their health-promoting properties for various conditions, including cancer, cardiovascular diseases, and neurological disorders. However, a critical analysis of the current research landscape reveals significant gaps that limit these promising compounds' clinical translation and efficacy.
Two significant challenges stand out as follows: (1) the poor bioavailability and stability of many bioactive compounds in vivo and (2) the limited understanding of how individual variations, particularly in gut microbiome composition, influence the efficacy of bioactive interventions. Additionally, there is a growing consensus that the future of nutrition science lies in personalized approaches that account for individual genetic, metabolic, and microbiome profiles.
This Special Issue aims to address these interconnected research gaps by focusing on innovative delivery systems for bioactive compounds and their interactions with the gut microbiome. The ultimate goal is to advance personalized nutrition approaches.
This Special Issue will bring together cutting-edge research on the following topics:
- Novel delivery systems for bioactive compounds that enhance bioavailability, stability, and targeted delivery;
- Microbiome–bioactive interactions that influence the metabolism, bioavailability, and efficacy of bioactive compounds;
- Personalized nutrition approaches that leverage individual variations in response to bioactive compounds;
- Synergistic effects between multiple bioactive compounds and the microbiome.
Prof. Dr. Ramona Suharoschi
Dr. Adriana Fodor
Dr. Oana Lelia Pop
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- bioactive compounds
- delivery systems
- gut microbiome
- personalized nutrition
- bioavailability
- encapsulation technologies
- microbiome–bioactive interactions
- targeted delivery
- precision nutrition
- synergistic interactions
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