Recent Advances in 3D Tumor Models for Cancer Research
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 136
Special Issue Editors
Interests: regenerative medicine; tissue engineering; nanoparticles; tumor therapy; cell isolation; primary cell culture
Special Issues, Collections and Topics in MDPI journals
Interests: scaffolds for regenerative medicine; electrospinning; thermally induced phase separation; hydrogels; bioprinting; organ-on-chip; bionanocomposites
Special Issues, Collections and Topics in MDPI journals
Interests: extracellular vesicles; exosomes; cancer biochemistry; tumor microenvironment; drug delivery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Three-dimensional (3D) cancer models have emerged as a promising approach to bridging the gap between traditional 2D systems and in vivo studies. These models, which include spheroids, assembloids, organoids, scaffolds, and organ-on-chip systems, more accurately mimic physiological conditions by incorporating not only cancer cells but also key components of the tumor microenvironment, such as cancer-associated fibroblasts (CAFs), immune and endothelial cells, components of the extracellular matrix, and other physiochemical stimuli. These advanced systems enable a deeper investigation of the physiological and biochemical pathways underlying tumor development and progression, serving as optimal platforms for drug screening and evaluation. This multidisciplinary field spans areas like biochemistry, cancer research, bioengineering, medicine, molecular biology, and pharmacology.
As guest editors, we warmly invite academic and industry researchers to submit high-quality reviews or original articles. Contributions should address key challenges and advancements, emphasizing the latest developments and cutting-edge strategies in 3D cancer modeling.
We look forward to your contributions.
Dr. Simona Campora
Dr. Francesco Lopresti
Dr. Alessandra Lo Cicero
Guest Editors
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Keywords
- 3D systems
- cancer research
- spheroids
- organoids
- organ-on-chip
- scaffolds
- tissue engineering
- biomedical technologies
- tumor microenvironment
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