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New Insights into Adipose Tissue Metabolic Function and Dysfunction 3.0

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 451

Special Issue Editor

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Guest Editor
Department of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy
Interests: pharmacology; natural products; oxidative stress; inflammatory disease; atherosclerosis; metabolic disease; neurodegenerative diseases; autophagy; proliferation and differentiation process
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Special Issue Information

Dear Colleagues,

Adipose tissue is widely known as an endocrine organ that can modulate systemic metabolism thanks to its effects on energy storage, adipokine production, and adaptive thermogenesis. This endocrine function is carried out in various organs, such as the liver, kidney, pancreas, and brain, and thus contributes to homeostatic regulation, energy balance, insulin sensitivity, and vascular–endothelial function.

The dysregulation of adipocyte differentiation, metabolism, and endocrine functions leads to adipose tissue dysfunction, which triggers the activation of molecular pathways involved in the physiopathology of overall metabolic diseases, such as obesity, inflammation, insulin resistance, and type 2 diabetes.

New therapeutic approaches targeting adipose tissue and its signaling molecules and heterogeneity could provide potential advances in understanding its pathophysiology and in treating several metabolic syndromes.

This Special Issue of the International Journal of Molecular Sciences entitled “New Insights into Adipose Tissue Metabolic Function and Dysfunction” aims to compile original research papers and/or relevant updates within the literature on new insights into the pathogenesis, molecular pathways, and beneficial effects of novel and safe treatments for metabolic diseases associated with adipose tissue dysfunction. In Volume II and Volume I, we have already published many excellent manuscripts and have high visibility and citations. We welcome you to read them and seek your contributions (comprehensive review or original article, etc.) to Volume III.

Dr. Federica Mannino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • inflammation
  • browning
  • thermogenesis
  • adipogenesis
  • diabetes
  • adipokines
  • energy storage
  • insulin resistance
  • obesity
  • lipolysis

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Published Papers

This special issue is now open for submission.
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