Adrenal Diseases and Tumors: Molecular Mechanisms, Genetics and Novel Treatments
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (20 March 2023) | Viewed by 2534
Special Issue Editor
Interests: adrenal insufficiency; adrenocortical adenoma; adrenocortical cancer; phechromocytoma; pathogenesis; genetics; treatment
Special Issue Information
Dear Colleagues,
The International Journal of Molecular Sciences (IF: 6.208, ISSN 1422-0067) is currently running a Special Issue, entitled "Adrenal Diseases and Tumors: Molecular Mechanisms, Genetics and Novel Treatments”. I am serving as Guest Editors for this Issue. I am interested in original scientific manuscripts and reviews analyzing the clinical aspects of adrenal diseases and tumors, the genetic and molecular defects of such diseases and tumors and the novel therapeutic options and targets for the patients. In the last few years, the expanding use of massive parallel sequencing has greatly increased the discovery of new genetic etiologies for adrenal diseases and syndromes associated with adrenal tumors.
Pheochromocytomas and paragangliomas are associated with germline defects in around 50% of cases (up to 70% in children with these tumors). Similarly, the genetic aspects of several adrenal diseases, such as primary adrenal insufficiency, adrenal hyperplasias and cancer, have significantly expanded. This recent evidence supports the importance of molecular pathogenesis to guide surveillance and define new molecular targets for diagnosis and therapy.
Prof. Dr. Madson Q. Almeida
Guest Editor
Manuscript Submission Information
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Keywords
- adrenal insufficiency
- adrenocortical adenoma
- adrenocortical cancer
- phechromocytoma
- pathogenesis
- genetics
- treatment