Platelet Signaling and Coagulation

Dear Colleagues,

Circulating platelets are highly reactive cell types that respond to a myriad of environmental cues to form homotypic aggregates as well as heterotypic interactions with leukocytes and endothelia. These events not only support a spectrum of normal homeostatic processes such as blood vessel integrity, initiation of the coagulation cascade, and immunological responses, but also ischemic pathologies and coagulopathies. Signaling events within platelets are well understood, but new inputs and modulators are being identified that provide insight as to how platelets produce unique responses in vivo.

This Special Issue of the International Journal of Molecular Sciences, entitled “Platelet Signaling and Coagulation”, will emphasize signaling pathways leading to critical platelet functions in hemostasis, coagulopathy, and thrombosis. The goal is to provide a broad view of platelet reactivity at the molecular level in a variety of physiological contexts. We invite you to contribute original research or focused reviews on the above topics for this Special Issue. We particularly welcome submissions from postdocs, PhD students, and young researchers.

We look forward to reading about your insights and exciting discoveries that further advance our knowledge of this crucial cell type in health and disease.

Dr. Stephen P. Holly
Dr. Rinku Majumder
Guest Editors

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