Organoid Models: Advancing the Study of Disease Mechanisms and Nutritional Regulations
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 241
Editors
Interests: mycotoxins; intestinal development and health; hepatic lipid metabolism; neonatal growth and nutrition
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Organoids, which are miniature, simplified versions of organs, have garnered significant attention and widespread use in biological research. They are particularly valuable for studying disease mechanisms and nutritional regulation. Serving as a bridge between simple cell cultures and complex animal models, 3D organoids provide a more physiologically relevant environment than traditional 2D cultures.
These organoids can be generated from patient-derived, treated, or healthy stem cells, offering a powerful platform for disease modeling, drug candidate screening, therapeutic testing, and investigating nutrient metabolism and signaling pathways. Since the first intestinal organoid was established in 2009, they have been developed from a wide range of cell types and are now widely applied in diverse fields, including genetics, metabolism, infectious disease, cancer research, and nutrient studies.
The aim of this Special Issue is to deepen our understanding of the underlying physiological, pathological, nutritional, and immunological interactions in tissues and organs across different diseases or developmental stages. We welcome the submission of original research articles and reviews that advance our knowledge of disease mechanisms and nutritional regulation.
Prof. Dr. Xi Lin
Prof. Dr. Pinghuang Liu
Guest Editors
Manuscript Submission Information
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Keywords
- organoids
- disease mechanisms
- nutritional regulation
- disease modeling
- stem cells
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