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Bioactive Natural Products: From Molecular Mechanisms to Biological Function

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 7

Special Issue Editor


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Guest Editor
Laboratory of Health and life Sciences, Department of Drug Sciences, Faculty of Medicine and Pharmacy of Tangier, University AbdelMalek Essaadi Tetouan, Tetouan, Morocco
Interests: understanding how natural compounds modulate cellular functions; discovery of novel natural products/new promising plants sources; biological activity and therapeutic potential; omics-based and molecular docking to identify mechanisms of action and predict bioactivity
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Special Issue Information

Dear Colleagues,

Diseases such as cancer, degenerative diseases, HIV/AIDS, and diabetes are among the numerous global health issues that present challenges in modern medicine as it races to provide treatments. Safety, pharmacokinetics, and efficacy are just a few of the many factors that must be considered when choosing a drug candidate in the field of drug discovery.

This Special Issue presents recent advances in the research of bioactive natural products, focusing on how their molecular mechanisms translate into biological functions. The published papers will explore natural compounds from plants, microorganisms, marine species, and fungi, using biochemical and omics-based approaches to identify targets and clarify mechanisms such as antioxidant, anti-inflammatory, antimicrobial, and anticancer actions.

New natural sources, innovative extraction techniques, structural characterization, and the molecular mechanisms of new compounds will also be highlighted in this Special Issue. Contributions will demonstrate the continued importance of natural products as a rich source of therapeutic candidates and as powerful tools for understanding and modulating key biological pathways.

Dr. Noureddine El Aouad
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural products
  • molecular mechanism
  • biological activities
  • drug discovery

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Published Papers

This special issue is now open for submission.
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