Molecular Targets in Alzheimer’s Disease: From Mechanisms to Therapeutic Strategies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 104
Special Issue Editor
Special Issue Information
Dear Colleagues,
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, characterized by loss of memory and cognition. Understanding, the molecular mechanism underlying the progression of AD is essential to understanding the potential cause of disease. Investigating this mechanism can provide valuable insight into the development of targeted therapeutic strategy.
Aim: 1) To explain molecular mechanism behind Aβ deposition and Tau phosphorylation; 2) To study the potential role of inflammation in progression of AD pathology; 3) To identify early biomarkers for the diagnosis of AD.
Potential topic:
- The role of Amyloid-beta and Tau Interactions in AD associated neurodegeneration.
- Microglial in Alzheimer’s disease and its role in neuroinflammation.
- Mitochondrial fission and fusion in Alzheimer’s disease.
- Role of inflammation in early and late onset of Alzheimer’s disease and therapeutic implication.
- Neurovascular dysfunction and amyloid angiopathy in Alzheimer’s disease.
Dr. Mohammad Ejaz Ahmed
Guest Editor
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Keywords
- amyloid beta
- neurodegeneration
- neuroinflammation
- microglia
- mitochondrial dysfucntion
- oxidative stress
- molecular pathway
- biomarkers of AD
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