Special Issue "Environmental Factors and Lifestyle Influence on Human Health: The Contribution of Epigenetic Mechanisms"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Environmental Health".
Deadline for manuscript submissions: 31 May 2019
Prof. Dr. Valentina Bollati
EPIGET - Epidemiology, Epigenetics and Toxicology Lab -Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy
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Interests: epigenetics; DNA methylation; extracellular vesicles; microRNAs; mitochondrial copy number; telomere length; air pollution; heavy metals; benzene; cardiovascular and respiratory effects of air pollution
The term lifestyle includes different factors, such as diet, behaviour, stress, physical activity, working habits, smoking and alcohol consumption. Increasing evidence shows that environmental and lifestyle factors may be associated with a variety of human diseases, including cancer, cardiovascular, respiratory, autoimmune, and neurological diseases. The search for a possible mechanism able to explain such associations has repeatedly pointed to epigenetics as a possible bridge between exposure and disease development. Epigenetic mechanisms are, in fact, flexible genomic parameters that can change genome function under exogenous influence but also provide a mechanism that allows for the stable propagation of gene activity states from one generation of cells to the next. In addition to what is strictly classified as epigenetics (for example DNA methylation, histone modifications and chromatin remodelling) other mechanism (such as microRNAs, extracellular vesicles) are starting to emerge as fundamental in this complex topic.
The goal of this Special Issue is to expand the current state of knowledge on these topics, to focus on the current gaps and help in the near future to bridge these gaps.
You are invited to submit manuscripts for consideration in this Special Issue. Contributions focused on epigenetic mechanisms, functional studies, development of new molecular markers of exposures as well as their possible impact on disease development, will be welcome. Studies on in vitro and in vivo models, such as investigating populations of subjects/patients, will be considered.
Prof. Dr. Valentina Bollati
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- DNA methylation
- Extracellular vesicles
- Environmental exposures
- Lifestyle factors
- Risk markers