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2nd Edition of Inflammatory Diseases and Its Impact on Quality of Life

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Global Health".

Deadline for manuscript submissions: closed (6 April 2023) | Viewed by 6611

Special Issue Editors


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Guest Editor
Departamento de Dermatología, Instituto Biosanitario de Granada, 18012 Granada, Spain
Interests: clinical medicine; epidemiology; dermatology; immune-mediated inflammatory diseases; advanced therapies; quality of life
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Guest Editor
Head of Gastroenterology Department, Hospital Universitario Virgen de las Nieves, 18014 Granada, Spain
Interests: endoscopic retrograde cholangiopancreatography; endoscopy EUS; pancreatic diseases; cholangiocarcinoma; gastrointestinal endoscopy
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Head of Rheumatology Department, Hospital Universitario Marqués de Valdecilla de Santander, 39008 Santander, Cantabria, Spain
2. Department of Medicine, Universidad de Cantabria, 39005 Santander, Cantabria, Spain
Interests: rheumatic diseases; musculoskeletal disorders; rheumatoid arthritis inflammation; autoimmune disease; autoimmunity; psoriasis; cardiovascular; genetics; T lymphocytes
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

A Special Issue on inflammatory diseases and their impact on quality of life is being organized in the International Journal of Environmental Research and Public Health. For detailed information on the journal, please refer to https://www.mdpi.com/journal/ijerph.

The term immune-mediated inflammatory diseases covers a wide range of pathologies that can affect different apparatuses and systems of the body such as the joints, the intestinal tract or the skin and appendages. They are characterized by a chronic course with possible flare-ups. In recent decades, a revolution has taken place in their treatment with the appearance of biological drugs and other small molecules. In spite of this, in many cases, control of the disease is only partial. In this group of pathologies, evaluating the effectiveness of the treatment through its impact on the quality of life is fundamental. The impact of the disease varies according to personal characteristics and the environment of the individual. Identifying factors related to a better or worse quality of life, or the effect of different treatments, and evaluating the quality of life in the social environment of patients are issues of great importance. For these reasons, we are promoting this Special Issue focused on quality of life in inflammatory diseases with the aim of deepening, promoting and strengthening research in this area of knowledge.

New research papers, meta-analyses, reviews and case reports are welcome to be submitted to this Special Issue. The keywords listed below provide an outline of some of the possible areas of interest.

Dr. Alejandro Molina Leyva
Prof. Dr. Salvador Arias-Santiago
Dr. Eduardo Redondo Cerezo
Prof. Dr. Miguel Angel Gonzalez-Gay
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immune-mediated inflammatory diseases
  • dermatology
  • rheumatology
  • gastroenterology
  • ophthalmology
  • quality of life of patients
  • quality of life of cohabitants
  • physical health
  • mental health
  • sexual health
  • patient-reported outcomes
  • physical comorbidity
  • psychological comorbidity
  • life-changing decisions
  • therapeutics and quality of life
  • Crohn’s disease
  • ulcerative colitis
  • arthritis
  • spondylitis
  • psoriasis
  • hidradenitis suppurativa
  • alopecia areata
  • atopic dermatitis
  • uveitis

Related Special Issue

Published Papers (3 papers)

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Research

18 pages, 2583 KiB  
Article
Minimal Clinically Important Differences (MCID) for the Functional Assessment of Chronic Illness Therapy Fatigue Scale in Patients with Systemic Sclerosis
by Franciska Kiss, Nelli Farkas, Gabriella Nagy, Tünde Minier, Gábor Kumánovics, Réka Faludi, László Czirják and Cecília Varjú
Int. J. Environ. Res. Public Health 2023, 20(1), 771; https://doi.org/10.3390/ijerph20010771 - 31 Dec 2022
Cited by 1 | Viewed by 2195
Abstract
(1) Background: Systemic sclerosis (SSc) is characterized by significant fatigue, causing diminished quality of life (QoL). The aim of this study was to examine fatigue levels and their associations with clinical factors and determine the minimal clinically important difference (MCID) value for the [...] Read more.
(1) Background: Systemic sclerosis (SSc) is characterized by significant fatigue, causing diminished quality of life (QoL). The aim of this study was to examine fatigue levels and their associations with clinical factors and determine the minimal clinically important difference (MCID) value for the Functional Assessment of Chronic Illness Therapy Fatigue Scale (FACIT-FS). (2) Methods: A total of 160 SSc patients and 62 individuals without SSc were followed-up over a 12-month period by measuring the FACIT-FS and the Visual Analogue Scale and the Short Form 36 Vitality Score analyzing changes in exhaustion. (3) Results: Fatigue was strongly correlated with HRQoL, level of pain, emotional disorders, physical capability and functionality. The MCID values for FACIT-FS were calculated as −3 for deterioration and +4 for improvement after a 12-month follow-up. The predictors of improvement of fatigue from baseline parameters were the significant disease activity, the patients’ poorer functionality and the short disease duration. Patients with scleroderma-related interstitial lung disease at baseline had approximately tripled risks for worsening fatigue. The independent influential factors regarding the changing of FACIT-FS were improving or worsening in the same direction in reference to physical condition, gastrointestinal and emotional factors. (4) Conclusions: Fatigue is a multi-dimensional symptom, which is strongly correlated to HRQoL. MCID values of FACIT-FS can be useful tools in monitoring the changes of HRQoL in clinical trials and in daily practice among patients with SSc. Full article
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12 pages, 814 KiB  
Article
Flare-Ups in Crohn’s Disease: Influence of Stress and the External Locus of Control
by María José de Dios-Duarte, Andrés Arias, Carlos Durantez-Fernández, Virtudes Niño Martín, Elena Olea, María Ángeles Barba-Pérez, Lucía Pérez-Pérez, Rosa M. Cárdaba-García and Ana Barrón
Int. J. Environ. Res. Public Health 2022, 19(20), 13131; https://doi.org/10.3390/ijerph192013131 - 12 Oct 2022
Cited by 6 | Viewed by 1815
Abstract
(1) Background: The aim of this study was to explore the role of perceived stress and the health locus of control in Crohn’s disease and their influence upon the development of flare-ups of this disease. (2) Methods: Stress and the external locus of [...] Read more.
(1) Background: The aim of this study was to explore the role of perceived stress and the health locus of control in Crohn’s disease and their influence upon the development of flare-ups of this disease. (2) Methods: Stress and the external locus of control were evaluated in a sample of 64 Crohn’s patients (flare-up phase versus latency phase). The perceived stress scale (PSS-14) and the multidimensional health locus of control scale were the measurement instruments used. (3) Results: The results indicate that the patients have high stress levels during a flare-up (26.13; 27.44; 28.79; 29.67); high stress levels (28.07; 29.67; 27.44; 28.07) if they have a high external locus of control; and that the external locus of control and stress levels have a significant influence upon the existence of flare-ups in those patients with low external locus of control levels (χ2 = 11.127; df = 1: p < 0.001). (4) Conclusions: Actions aimed at reducing stress and external locus of control levels are necessary in Crohn’s disease. Full article
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8 pages, 338 KiB  
Article
The Impact of Sleep Quality on Mood Status and Quality of Life in Patients with Alopecia Areata: A Comparative Study
by Manuel Sánchez-Díaz, Pablo Díaz-Calvillo, Alberto Soto-Moreno, Alejandro Molina-Leyva and Salvador Arias-Santiago
Int. J. Environ. Res. Public Health 2022, 19(20), 13126; https://doi.org/10.3390/ijerph192013126 - 12 Oct 2022
Cited by 3 | Viewed by 1915
Abstract
Alopecia Areata (AA) is a chronic condition which has been associated with poor quality of life and mood status disturbances. The aim of this study is to compare the sleep quality between AA patients and controls, and to analyze the impact of poor [...] Read more.
Alopecia Areata (AA) is a chronic condition which has been associated with poor quality of life and mood status disturbances. The aim of this study is to compare the sleep quality between AA patients and controls, and to analyze the impact of poor sleep quality on patients with AA regarding mood status disturbances, quality of life and sexuality. A cross-sectional study including patients suffering from mild-to-severe AA and sex- and age-matched healthy controls was performed. Socio-demographic and clinical variables, sleep quality, quality of life, sexual disfunction, anxiety, depression and personality were collected using validated questionnaires. A total of 120 participants (60 patients and 60 controls) were included. Patients with AA showed worse sleep scores than controls (p = 0.003), as well as higher rates of anxiety and depression (p < 0.05). After a multivariate analysis, a worse sleep quality was found to be linked to anxiety, depression, a poorer quality of life and a type D personality score independently of the disease severity. In light of the results, patients with AA have a worse sleep quality than healthy controls. A poor sleep quality is associated with anxiety, depression and a worse quality of life, therefore being a general marker of a poor quality of life. Screening for sleep disturbances in specialized units could be useful to detect patients who could benefit from additional psychological support. Full article
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