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Special Issue "Virulence Gene Regulation in Bacteria"
Deadline for manuscript submissions: closed (31 August 2016).
School of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV 89154-4004, USA
Interests: mechanisms of bacterial pathogenesis; bacterial transcription and gene regulation; protein localization studies; bacterial motility and chemotaxis; outer membrane proteases; bacterial resistance to cationic antibacterial peptides; extra-host survival of bacterial pathogens
The precise control of virulence gene expression underpins the pathogenicity of many important bacterial pathogens. This regulatory control can be triggered by diverse stimuli including rising bacterial numbers, environmental stressors encountered in the host environment or even physical parameters, like direct contact between a bacterium and its host. Responding to these cues are suites of transcription factors and regulatory RNA molecules that function alone or in combination to up- or down-regulate the synthesis or longevity of transcripts. While the complexity of the regulatory networks and the variety of molecular mechanisms employed is impressive, their exquisite coordination is undoubtedly central to the physiology and the pathogenic nature of these bacteria. An improved understanding of these regulatory events has the potential to reveal processes unique to bacteria that can be exploited as novel drug targets. In a single issue of Genes in Fall of 2016, we would like to convey our current understanding of virulence gene regulation in bacteria by showcasing some of the best research from around the world. We welcome reviews and original articles in the area of transcriptional regulation and post-transcriptional control of bacterial virulence genes that are imparted by DNA binding proteins, small regulatory RNAs or even the transcripts themselves.
Assoc. Prof. Dr. Helen J. Wing
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Bacterial virulence
- gene expression
- transcriptional regulation
- mRNA decay
- subcellular localization of transcripts
- two component regulatory systems
- nucleoid structuring proteins
- regulation of bacterial secretion
- regulation of antibiotic resistance
- post-transcriptional regulation
- regulation of toxin production