Special Issue "Membrane Proteins in Parasitic Protozoa"
Deadline for manuscript submissions: closed (31 May 2018) | Viewed by 53562
Interests: metabolism; parasitic diseases; molecular parasitology; protozoology; evolutionary parasitology; pathogenesis; NTD drug development; Entamoeba vesicular traffic
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2. Visiting Researcher, Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Interests: mitosome; mitochondrion related organelles; membrane proteins; beta barrel proteins; Entamoeba histolytica
The cell and its organelles are bound by membrane barriers, which are lined with proteins that perform various functions. In parasites, divergent mechanisms exist as a means to evade the host immune system, with some involving membrane proteins that play roles related to metabolism, transport, signaling, and pathogenesis among others. Intracellular membrane proteins, especially in parasite-specific organelles, are also known to play various essential roles in protein and metabolite transport, lipid exchange, organelle dynamics, organelle–organelle crosstalk, and biogenesis.
The significance of the diverse roles of membrane proteins have attracted extensive researches on this field, as the discovery and further understanding of membrane in human parasites, and their roles will immensely contribute to the fields of parasite cell biology and evolution in general, and could support the development of new parasite-specific drugs. In this Special Issue of Genes, the focus is on studies related to parasite membrane proteins, from the mechanisms of genetic acquisition, phylogeny and evolution, to structural and functional elucidations.
We cordially invite researchers working actively in these fields to submit their original research or review manuscripts to this research topic of membrane proteins in parasitic organisms.Prof. Tomoyoshi Nozaki
Dr. Herbert J. Santos
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- membrane proteins
- host-parasite interaction