Special Issue "How Do New Genes Originate and Evolve?"
Deadline for manuscript submissions: closed (15 September 2022) | Viewed by 23835
Interests: New gene evolution, including rate, pattern, molecular mechanisms, and evolutionary forces. The Long lab is exploring the evolution of gene functionality and protein diversity by de novo genes and investigating evolutionary forces that drive new gene origination, ranging from adaptive evolution to sexual selection to sexual conflict leading to functional imperfection.
Interests: The general topics of interest are evolutionary genomics and molecular evolution. In particular the Betrán lab focusses on the origin of functional innovations in the genomes. This includes the study of retrogenes (i.e., gene duplicates produced by means of an mRNA intermediate) and domesticated transposable element proteins.
Every species has its own distinct genetic makeup and they underlie the great diversity of molecular functions and morphologies. How new genes with functional novelties originate is a fundamental evolutionary problem, having attracted a wide range of attention from scientists to audiences outside the scientific community. With the advent of the high throughput genome sequencing, powerful gene editing and precision molecular biological analyses, the evolutionary and functional properties of new genes are being unveiled. Consequently, the study of new genes has become more accessible and feasible, not only for model species but also for non-model organisms, revealing their evolution and often functional importance. The scientific questions that are explored to understand new genes can be enounced but they are not limited to: How do new genes originate and for what functions? What evolutionary forces operate during their acquisition? Are there any patterns or rules in the molecular mechanisms responsible for the origination of new genes? What are the rates of new gene origination in different lineages? We hope to receive a diverse set of submissions that represent the diversity of life and systems where those questions are being addressed.
Prof. Manyuan Long
Prof. Esther Betran
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- New genes
- Gene duplication
- De novo genes
- Origin of sex-specific genes
- Transposable element protein domestication
- Viral protein domestication
- Horizontal gene transfer