Ancient and Archaic Genomes
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Population and Evolutionary Genetics and Genomics".
Deadline for manuscript submissions: closed (31 January 2021) | Viewed by 46902
Special Issue Editors
Interests: ancient DNA; human evolution; human population genetics; forensics genetics; wildlife forensics genetics
Interests: molecular anthropology and paleogenetics; recovery and analysis of ancient and degraded DNA from human, animal and plant ancient remain. NGS methods; phylogenetic analysis; genetic history of past populations; ancient microbiome reconstruction; molecular and genetic methods applied to the preservation and valorization of cultural heritage
Interests: molecular anthropology and paleogenetics; recovery and analysis of ancient and degraded DNA from human, animal and plant ancient remain; NGS methods; phylogenetic analysis; genetic history of past human populations; domestication processes; molecular and genetic methods applied to the preservation and valorization of cultural heritage
Special Issue Information
The development of high-throughput sequencing has triggered a revolution in the study of ancient DNA. In the last decade, methodological advances have allowed researchers to overcome some of the limits linked to the degradation and preservation of nucleic acids, improving the capacity of recovery and analysis of the ancient molecules. This fact, along with a wider accessibility to the Next-Generation Sequencing platforms, has contributed to increase the number of genomic studies on ancient remains. The applications of paleogenomics span several research fields. Genomic data from archaic hominins are providing exceptional information for the study of human evolution, detecting interbreeding between different human forms. Genome-level studies of prehistorical and historical human samples are helping to understand genetic variability through time and to unravel past population dynamics. Genomic data from ancient animal and plant remains allow researchers to reconstruct the evolutionary history of wild and domesticated populations and directly observe genetic changes linked to natural and artificial selection, and contribute to management decisions in conservation projects. Pathogen paleogenomics is leading to the discovery of extinct microbial lineages and to the characterization of the evolutionary history of microorganisms that are still relevant today.
This Special Issue will collect reviews and original contributions concerning the study of ancient and archaic genomes from different organisms, considering accomplishments and challenges, methodological approaches, bioinformatics and analytical tools, current status, and future prospects of paleogenomic research.
Sincerely
Prof. David Caramelli
Prof. Martina Lari
Dr. Stefania Vai
Guest Editors
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Keywords
- Next-Generation Sequencing (NGS)
- ancient DNA
- paleogenomics
- archaic humans
- archeogenetics
- extinct species
- conservation genomics
- domestication
- paleopathogens
- evolutionary genomics
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