Special Issue "Stem Cells Application in Clinical Practice: Advances and Challenges"
Deadline for manuscript submissions: closed (25 October 2019).
Interests: regenerative medicine; stem cells; tissue engineering
2. St. Catherine Hospital and Universities of Split, Osijek and Rijeka, 49210 Zabok, Croatia
Interests: personalised medicine; stem cells; pharmacogenetics; paediatrics; DNA analysis; human diseases; bone diseases; forensic genetics; population genetics
The use of stem cells (SCs) and, in general, of synthetic biology approaches to treat disease has significant promise. Likewise, enthusiasm for SC therapy is running high within the medical community of researchers and patients. Among the most promising SCs are mesenchymal fetal and adult stem cells, such as those derived from cord blood, bone marrow, and fat, which may possess anti-inflammatory, immunomodulatory, antiapoptotic, or angiogenic properties. Amnion-derived stem cells (ADSCs) have more recently been isolated. ADSCs are multipotent stem cells with intermediate characteristics between embryonic and adult stem cells, showing the ability to differentiate into cell types from all three germ layers.
Many aspects concerning the biology of stem cells, their differential potential in vitro and in vivo, as well as their mechanisms of action remain unsolved. However, the use of SCs requires a high level of competence during all phases of the procedure, from cell isolation to clinical trial evaluation. Finally, the clinical application of SCs fosters numerous ethical and safety discussions.
Therefore, this Special Issue of Genes will place a special emphasis on basic, translational, and clinical research in stem cell therapeutics and regenerative medicine. We welcome research articles as well as reviews addressing different issues related to stem cells.
Topics of interest include but are not limited to the following:
- Sources, isolation, nature, and molecular characterization of SCs
- Phenotyping of SCs
- Developmental potential, biological functions, and therapeutic uses of SCs
- Clinical studies using stem cells
- Adult and fetal stem cells
Prof. Anthony Atala
Prof. Dragan Primorac
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- stem cells
- human disease
- mesenchymal stem/stromal cells
- adult stem cells
- fetal stem cells
- stromal vascular fraction (SVF)
- stem cell therapy
- regenerative medicine