Genetics of Ocular Motility, Strabismus and Amblyopia

Dear Colleagues,

Defects in ocular motility, strabismus and amblyopia are a heterogenous group of conditions that occur in both adult and paediatric populations. The large phenotypic variability within these clinical groups have made elucidating genetic contributions (and molecular diagnoses) difficult for many of these conditions where there is a suspicion of heritability. Much of the current literature concentrates on incomitant myogenic, neurogenic, and cranial nerve misrouting disorders, with limited work involving concomitant strabismus. While clinical phenotypes are well-described in strabismus, ocular motility and amblyopia, mono- and polygenetic contributions are much less well-understood. With recent advances in the genetic diagnostics and therapies in ophthalmology, there is a growing unmet need for a deeper understanding of the genetic contributions to these life-altering conditions to facilitate personalised patient care as we move into the genetic age.

In this Special Issue, we welcome reviews and original articles centred on the study of ocular motility, strabismus, and amblyopia. These can include, but are not limited to, genetics and the molecular mechanisms of disease, the diagnosis and clinical phenotyping of patients, epidemiology, ethnic variability, preclinical research in the area, and clinical studies and trials of new treatments.

We look forward to receiving your contributions.

Dr. Vijay Tailor
Dr. Michael Gilhooley
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.