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RNA Interference
This special issue belongs to the section “Molecular Genetics and Genomics“.
Special Issue Information
Dear Colleagues,
In the last ten years fewer techniques can have revolutionised life science research more than the ability to carry out gene downregulation studies in cultured cells in a straightforward and robust manner. The technique of RNA interference is now routinely applied in the study of probably all cellular processes and events. Furthermore, its ease of use and accessibility has resulted in it now being a mainstream tool in high-throughput functional genomics approaches to systematically study gene function. Perhaps also equally exciting is the use of RNAi in a therapeutic context, and efforts to improve the delivery of RNAi molecules to specific tissues and cells in vivo is now well advanced.
This special issue serves to highlight the importance of this technique in the life sciences. We are particularly keen to hear of new advances in the use of RNAi in cellular assays to understand gene function, however research or review articles on any topic within the RNAi field will be considered. We look forward to your contributions.
Prof. Dr. Jeremy C. Simpson
Guest Editor
In the last ten years fewer techniques can have revolutionised life science research more than the ability to carry out gene downregulation studies in cultured cells in a straightforward and robust manner. The technique of RNA interference is now routinely applied in the study of probably all cellular processes and events. Furthermore, its ease of use and accessibility has resulted in it now being a mainstream tool in high-throughput functional genomics approaches to systematically study gene function. Perhaps also equally exciting is the use of RNAi in a therapeutic context, and efforts to improve the delivery of RNAi molecules to specific tissues and cells in vivo is now well advanced.
This special issue serves to highlight the importance of this technique in the life sciences. We are particularly keen to hear of new advances in the use of RNAi in cellular assays to understand gene function, however research or review articles on any topic within the RNAi field will be considered. We look forward to your contributions.
Prof. Dr. Jeremy C. Simpson
Guest Editor
Keywords
- RNAi
- siRNA
- shRNA
- gene downregulation
- functional genomics
- cellular assays
- RNA therapeutics
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Genes - ISSN 2073-4425