Cell-Free Nucleic Acids as Diagnostic Tools

Dear Colleagues,

Historically, blood samples have been used to assess dynamic changes in clinically relevant biomolecules to diagnose disease. Discoveries leading to the identification of cell-free (cf) nucleic acids (NAs) in liquid biopsies have opened possibilities in predicting future disease as cfNAs can not only be biomarkers but also mediators or regulators of pathophysiological processes. Intriguingly, unlike other biomolecules such as SNP profiles from blood, and circulating molecules such as mRNAs, microRNAs, and circRNAs, cfDNAs present dynamic changes over the lifetime, and possibly across generations. This Special Issue aims to be the leading channel for publishing original reports, reviews, meta-analyses/systematic reviews, and short reports on cfNAs as biomarkers and/or regulators of human health. We look forward to submissions that not only demonstrate new molecular candidates/signatures but also validate existing research.

Dr. Anandwardhan A. Hardikar
Dr. Mugdha Joglekar
Guest Editors

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• cfNAs
• cfDNAs
• circulating nucleic acids
• biomarkers of human health
• liquid biopsies
• diagnostic tools