Genetics of Parkinson’s Disease around the World

Dear Colleagues,

Parkinson’s disease (PD) is a genetically complex neurodegenerative condition influenced by intricate interactions between genetic and environmental factors. It encompasses both monogenic and idiopathic forms, with a growing number of genes known to contribute to its multifaceted aetiology. However, research into Parkinson’s genetics has predominantly focused on individuals of European ancestry, limiting the applicability of findings to broader ethnic and geographic populations.

This Special Issue aims to bridge the knowledge gap in PD genetics within under-represented human populations. We aim to publish studies featuring genetic discoveries related to PD aetiology and its implications in diverse demographics. Our goal is to illuminate the intricate genetic landscape governing PD manifestation and progression.

Within this Special Issue, we will prioritise unravelling the genetic variants, mutations, and risk factors specific to under-represented populations. Understanding the differential gene expression levels associated with PD among diverse ethnicities is crucial in identifying the related biological processes and shared genomic architectures.

We invite contributions exploring any aspect related to the genetics of Parkinson’s disease across diverse populations. Structural, functional, computational, clinical, and experimental studies focusing on either familial or idiopathic PD are welcome.

Join us in this endeavour to shed light on the genetic intricacies of PD across human populations, facilitating a more inclusive and comprehensive understanding of this disease's genetic architecture and aiding in developing tailored approaches to PD management and treatment.

Dr. Miguel E Rentería
Dr. Katarzyna Smilowska
Dr. Rauan Kaiyrzhanov
Dr. Wael Mohamed Yousef Mohamed
Guest Editors

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• Parkinson’s disease
• human genetics
• movement disorders
• neurology
• under-represented populations
• genetic variants
• healthcare disparities
• molecular pathways
• personalized medicine