New Insights on Fish Immunology

A special issue of Fishes (ISSN 2410-3888).

Deadline for manuscript submissions: closed (15 November 2021) | Viewed by 9109

Special Issue Editors


E-Mail Website
Guest Editor
Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100 Murcia, Spain
Interests: fish immunology; immunostimulation; pollution; diseases; cell biology
Special Issues, Collections and Topics in MDPI journals

E-Mail
Guest Editor
Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100 Murcia, Spain

Special Issue Information

Dear Colleagues,

A Special Issue entitled “New Insights in Fish Immunology” is being launched by the journal Fishes. Research on fish immunology started in the 1960s and 1970s and was initially focused on humoral responses and descriptions of immune organs and cells. Thorough research on T cell responses and innate immunity began later and prompted subsequent studies on cell regulation and immune cell surface receptors. Afterward, attention turned particularly to the interaction between the immune system and pathogens, providing the basis for works on fish vaccination and the selection of disease-resistant fish. At the same time, assays were developed to determine the immunomodulatory properties of various dietary ingredients such as vitamins, molecules present in prokaryotic cells, bioactive plant molecules, and probiotics. These researches were mainly carried out on a limited number of bony fish species with high economic interest due to the great development of aquaculture practices. Fish immunology has emerged as a flourishing research field towards the end of the 20th century.

With this background, this Special Issue aims to present a collection of papers on new advances in fish immunity. Topics of interest include: the relationships between immune and stromal cells, innate immunity and inflammation, hypersensitivity, immune regulation, infectious diseases and host response, maternal passive immunity, fish-to-fish passive immunization, systems immunology.

Similarly, understanding the activation and differentiation of immune cells is essential for understanding immunology. Results from novel immunological methods or recent technical advances, such as single-cell or single-nucleus sequencing and imaging mass cytometry, could also foster new insights into the cell biology of immune cells, including cell differentiation or maturation. The aim of this Special Issue is to improve our knowledge of fish immunity in both health and disease and help to promote the adoption of sustainable and welfare-oriented therapeutics and prophylactic strategies for aquaculture practices.

Prof. Dr. Maria Angeles Esteban
Dr. Cristobal Espinosa Ruiz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fishes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

15 pages, 6967 KiB  
Communication
The Early Immune Response of Lymphoid and Myeloid Head-Kidney Cells of Rainbow Trout (Oncorhynchus mykiss) Stimulated with Aeromonas salmonicida
by Fabio Sarais, Ruth Montero, Sven Ostermann, Alexander Rebl, Bernd Köllner and Tom Goldammer
Fishes 2022, 7(1), 12; https://doi.org/10.3390/fishes7010012 - 7 Jan 2022
Cited by 3 | Viewed by 3156
Abstract
The teleost head kidney is a highly relevant immune organ, and myeloid cells play a major role in this organ’s innate and adaptive immune responses. Because of their complexity, the early phases of the innate immune reaction of fish against bacteria are still [...] Read more.
The teleost head kidney is a highly relevant immune organ, and myeloid cells play a major role in this organ’s innate and adaptive immune responses. Because of their complexity, the early phases of the innate immune reaction of fish against bacteria are still poorly understood. In this study, naïve rainbow trout were stimulated with inactivated A. salmonicida and sampled at 12 h, 24 h and 7 d poststimulation. Cells from the head kidney were magnetically sorted with a monoclonal antibody mAB21 to obtain one (MAb21-positive) fraction enriched with myeloid cells and one (MAb21-negative) fraction enriched with lymphocytes and thrombocytes. The gene expression pattern of the resulting cell subpopulations was analysed using a panel of 43 immune-related genes. The results show an overall downregulation of the complement pathway and cytokine production at the considered time points. Some of the selected genes may be considered as parameters for diagnosing bacterial furunculosis of rainbow trout. Full article
(This article belongs to the Special Issue New Insights on Fish Immunology)
Show Figures

Graphical abstract

13 pages, 2233 KiB  
Article
Wound-Induced Changes in Antioxidant Enzyme Activities in Skin Mucus and in Gene Expression in the Skin of Gilthead Seabream (Sparus aurata L.)
by Cristóbal Espinosa-Ruíz and María Ángeles Esteban
Fishes 2021, 6(2), 15; https://doi.org/10.3390/fishes6020015 - 18 Apr 2021
Cited by 16 | Viewed by 4296
Abstract
This study investigated the antioxidant enzyme activities in the skin mucus of gilthead seabream (Sparus aurata L.) at 3 and 7 days post-wounding (dpw). The expression levels of the genes that encode stress proteins (grp170, grp94, grp75, sod [...] Read more.
This study investigated the antioxidant enzyme activities in the skin mucus of gilthead seabream (Sparus aurata L.) at 3 and 7 days post-wounding (dpw). The expression levels of the genes that encode stress proteins (grp170, grp94, grp75, sod and hsp70) and skin regeneration-related proteins (tf, igf1, tgfb1, der1, apo1 and erdj3) in the skin also were determined. Mucus and skin samples were obtained from the left and right flanks of non-wounded and wounded fish. In both flanks of the wounded fish, catalase and glutathione reductase activities in the skin mucus increased (p < 0.05) at 3 and 7 dpw (100 ± 31% and 111 ± 25%, respectively), whereas superoxide dismutase activity increased (p < 0.05) only at 7 dpw (135 ± 15%). The expression levels of stress proteins in the skin of the wounded flank of the wounded fish mainly increased at 7 dpw (grp170 increased to 288 ± 85%, grp94 to 502 ± 143%, grp75 to 274 ± 69%, sod to 569 ± 99%, and hsp70 increased to 537 ± 14%) (p < 0.05). However, the expression levels of the tissue regeneration-related genes varied depending on the flank investigated, on the experimental time, and on the gene studied. To the best of our knowledge, this is the first work to determine the effect of a wound in different skin parts of the same fish. Full article
(This article belongs to the Special Issue New Insights on Fish Immunology)
Show Figures

Figure 1

Back to TopTop