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Therapeutic Potential of Probiotics, Prebiotics, and Synbiotics in Advancing Aquaculture...
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Therapeutic Potential of Probiotics, Prebiotics, and Synbiotics in Advancing Aquaculture Health and Performance

A special issue of Fishes (ISSN 2410-3888).

Deadline for manuscript submissions: 31 October 2025 | Viewed by 2084

Special Issue Editors

Dr. Hien Van Doan

E-Mail Website
Guest Editor
Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand
Interests: aquaculture; immunostimulants; feed additives; fish nutrition; probiotics
Special Issues, Collections and Topics in MDPI journals
Dr. Seyed Hossein Hoseinifar

E-Mail Website
Guest Editor
Department of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran
Interests: aquaculture; immunomodulation; feed additives; aquaculture microbiology; microbiome; fish health
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Ehab El-Haroun

E-Mail
Guest Editor
Fish Nutrition Research Laboratory, Animal Production Department, Faculty of Agriculture, Cairo University, Cairo, Egypt
Interests: fish nutrition; prebiotic; probiotics and synbiotics; feed additives
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The sustainable advancement of aquaculture is increasingly dependent on the application of innovative biotic interventions such as probiotics, prebiotics, and synbiotics, which have emerged as essential tools for improving health, enhancing immune responses, and boosting the overall performance of aquatic species, and serve as sustainable alternatives to antibiotics and other conventional treatments. The growing body of research on these biotic agents highlights their potential to revolutionize disease management, enhance growth, and improve the resilience of farmed species under various aquaculture systems.

This Special Issue, entitled “Therapeutic Potential of Probiotics, Prebiotics, and Synbiotics in Advancing Aquaculture Health and Performance”, aims to compile high-quality research exploring the therapeutic roles of these biotic agents in aquaculture. It seeks to deepen our understanding of their mechanisms of action, synergistic effects, and practical applications, with a focus on improving the sustainability and efficiency of aquaculture practices worldwide.

We invite submissions of original research articles, reviews, and short communications that delve into the following topics:

  • Innovative applications and mechanisms: Studies on how probiotics, prebiotics, and synbiotics impact the growth, feed efficiency, immunity, and overall health of aquaculture species, including their underlying mechanisms.
  • Disease prevention and health management: Research on the role of biotics in preventing infections, enhancing disease resistance, and managing pathogens in aquaculture.
  • Synergistic and functional feed approaches: Insights into combined biotic applications and the development of functional feeds to support aquaculture health and performance.
  • Integration with advanced aquaculture systems: Evaluations of how these biotic agents can be effectively integrated with biofloc, recirculating aquaculture systems (RASs), and other sustainable aquaculture practices.
  • Omics and metagenomic insights: The use of advanced omics technologies to unravel the impacts of biotics on the gut microbiome, host physiology, and environmental interactions.
  • Safety, efficacy, and regulation: Studies addressing the safety, efficacy, and regulatory considerations of biotics in aquaculture.
  • Future trends and innovations: The exploration of novel strains, next-generation biotics, and future perspectives in aquaculture applications.

This Special Issue will serve as a platform showcasing cutting-edge research that drives the understanding and application of biotics in aquaculture, contributing to the industry’s shift towards more sustainable and healthier production systems. We welcome submissions from interdisciplinary studies encompassing microbiology, nutrition, immunology, and aquaculture technology.

Dr. Hien Van Doan
Dr. Seyed Hossein Hoseinifar
Prof. Dr. Ehab El-Haroun
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fishes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Important Details:

  • The Article Processing Charge (APC) for publication in this open-access journal is 2600 CHF (Swiss Francs).
  • Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • probiotics
  • prebiotics
  • synbiotics
  • aquaculture health
  • disease resistance
  • sustainable aquaculture
  • functional feeds

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

17 pages, 3293 KiB  
Article
Effects of Mango Seed (Mangifera indica) Powder on Growth Performance, Immune Response, Gut Morphology, and Gene Expression of Nile Tilapia (Oreochromis niloticus)
by Camilla Maria Fontana, Md Afsar Ahmed Sumon, Supreya Wannavijit, Anisa Rilla Lubis, Nuttapon Khongdee, Nguyen Vu Linh, Yuthana Phimolsiripol, Seyed Hossein Hoseinifar and Hien Van Doan
Fishes 2024, 9(12), 514; https://doi.org/10.3390/fishes9120514 - 16 Dec 2024
Viewed by 1716
Abstract
This study explored the effects of mango seed (MS) powder supplementation on the growth, immune response, gene expression, and intestinal morphology of Nile tilapia (Oreochromis niloticus) over an 8-week period. A total of 300 Nile tilapia fingerlings (average weight of 15.29 [...] Read more.
This study explored the effects of mango seed (MS) powder supplementation on the growth, immune response, gene expression, and intestinal morphology of Nile tilapia (Oreochromis niloticus) over an 8-week period. A total of 300 Nile tilapia fingerlings (average weight of 15.29 ± 0.05 g) were divided into five treatment groups and fed either a basal diet or one of four experimental diets containing MS powder at concentrations of 10 (MS10), 20 (MS20), 40 (MS40), and 80 (MS80) g kg−1. The results demonstrated that Nile tilapia fed MS-supplemented diets experienced significant improvements (p < 0.05) in weight gain (WG), specific growth rate (SGR), and survival rate (SR) compared to the control group (0 g kg−1 MS). The MS-treated groups also showed a significant increase (p < 0.05) in the height and branching of intestinal villi along the entire length of the intestine, as well as a significantly higher villus-to-crypt depth ratio (V/C), indicating enhanced intestinal health and functionality. Moreover, although MS supplementation did not increase peroxidase activity, it did lead to a significant increase (p < 0.05) in the activity of skin mucus and serum lysozyme, along with upregulated gene expression of immune-related (IL-1, IL-8, and LBP) and antioxidant genes (GST-α, GPX, and GSR). Polynomial regression analysis identified an optimal MS dosage of 36.43–45 g kg−1 for effectively improving growth, immunity, and immuno-oxidant gene expression in Nile tilapia. These results emphasize mango seed (MS) as a promising natural supplement for improving the diet of Nile tilapia and, potentially, other freshwater fish widely used in aquaculture. Full article
(This article belongs to the Special Issue Therapeutic Potential of Probiotics, Prebiotics, and Synbiotics in Advancing Aquaculture Health and Performance)
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