Feature Papers in Fermentation Process Design

Dear Colleagues,

The growing demand for energy and environmental consequences associated with their use plus persistent volatility in energy market prices over the past three decades have driven substantial efforts in bio-based research, particularly in the development of biofuels and biochemicals. Fermentation, commonly used for the production of both macro- and micromolecules, is a metabolic process in which microorganisms convert organic compounds under anaerobic or, in some cases, aerobic conditions, to new molecules. Indeed, fermentation is central to biological production of fuels, biopolymers, peptides, lipids, amino acids, antibodies, vitamins and a wide range of other value-added chemicals. Beyond bioproduction, fermentation plays important roles in food preservation and flavor development in some foods, as well as in chemical remediation and waste treatment, particularly in anaerobic digestion systems. Sometimes fermentation products are present at very low concentrations and yields, often requiring optimization to increase their yields. In some cases, the generated products inhibit the growth of producing microorganisms and therefore need to be removed in real time to allow continued synthesis of the desired fermentation products. Additionally, these fermentation products often require purification before they can be used. To achieve these goals, effective downstream processing and process modeling are essential. This Special Issue, therefore, aims to publish high-quality review, original research, and short communication articles spanning all aspects of fermentation and fermentation process designs.

Topics of interest for this Special Issue include, but are not limited to:

• Novel bioreactor and bioprocess designs;
• The production of macromolecules (e.g., enzymes, other proteins, antibodies, lipids and polysaccharides);
• The production of small molecules (e.g., ethanol, butanol, propanediol, butanediol, amino acids, peptides, and vitamins);
• The bioremediation of pollutants;
• Improved separation methods for the recovery of fermentation products;
• Advanced tools for monitoring and controlling bioreactors;
• Analyses of bioreactor performance.

Prof. Dr. Thaddeus Ezeji
Dr. Miguel Ladero Galán
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• process design
• fermentation optimization
• bioreactor performance
• scale-up
• scale-down
• microbial kinetics
• batch fermentation
• fed-batch fermentation
• continuous fermentation
• purification methods
• downstream processing of fermentation products
• bioprocess monitoring