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Diagnostics
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Update on Optical Coherence Tomography Angiography Imaging in Optic Neuropathies
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Update on Optical Coherence Tomography Angiography Imaging in Optic Neuropathies

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Biomedical Optics".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 1667

Special Issue Editor

Prof. Dr. Katarzyna Nowomiejska

E-Mail Website
Guest Editor
Chair and Department of General and Pediatric Ophthalmology, Medical University of Lublin, Lublin, Poland
Interests: ophthalmology; vitreoretinal surgery; eye trauma; retinal dystrophies; optic neuropathies; cataract surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the structural analyses of the retina and retinal nerve fiber layer (RNFL) using optical coherence tomography (OCT ) have been proven to be an excellent tool for detecting and monitoring axonal loss and neurodegeneration in patients with different diseases of the retina and optic nerve. Moreover, optical coherence tomography angiography (OCT-A) provides non-invasive and reliable data which allows for measurements of microvascular changes in the retina and choroid as well as RNFL defects. OCT-A facilitates en-face visualization of the retinal circulation into the superficial and deep vascular networks supplying the various retinal layers. As a new diagnostic tool, OCT-A has been widely used in retinal vascular diseases; however, publications on the utility of OCCT-A in optic neuropathies are scarce.

This Special Issue aims to evaluate OCT-A in optic neuropathies of different origin, including traumatic, ischemic (arteritic and non-arteritic), inherited (Leber hereditary optic neuropathy, dominant optic neuropathy), inflammatory, demyelinated (multiple sclerosis, neuromyelitis optica), compressive (optic nerve tumors) and toxic. Additionally, reports on using OCT-A in congenital optic disc anomalies, as optic disc drusen and optic hypoplasia, are welcome. Moreover, studies on retinal microvasculature in optic disc edema and optic disc atrophy are of our interest. The results of the studies on OCT-A imaging in optic neuropathies will provide a background for future more detailed differentiation between optic neuropathies of different origin.

Prof. Dr. Katarzyna Nowomiejska
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • optic neuropathies
  • OCT-A
  • optic disc edema
  • optic atrophy

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Published Papers (1 paper)

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Research

17 pages, 3674 KiB  
Article
Vascular Changes in the Macula of Patients after Previous Episodes of Vision Loss Due to Leber Hereditary Optic Neuropathy and Non-Arteritic Ischemic Optic Neuropathy
by Katarzyna Nowomiejska, Patrycja Lesiuk, Agnieszka Brzozowska, Katarzyna Tońska and Robert Rejdak
Diagnostics 2023, 13(10), 1726; https://doi.org/10.3390/diagnostics13101726 - 12 May 2023
Viewed by 1277
Abstract
Purpose: to assess the vasculature and thickness of the macula using OCT-A in patients who had experienced a previous episode of Leber hereditary optic neuropathy (LHON) or non-arteritic anterior ischemic optic neuropathy (NA-AION). Methods: twelve eyes with chronic LHON and ten eyes with [...] Read more.
Purpose: to assess the vasculature and thickness of the macula using OCT-A in patients who had experienced a previous episode of Leber hereditary optic neuropathy (LHON) or non-arteritic anterior ischemic optic neuropathy (NA-AION). Methods: twelve eyes with chronic LHON and ten eyes with chronic NA-AION and eight NA-AION fellow eyes were examined using OCT-A. The vessel density was measured in the superficial and deep plexus of the retina. Moreover, the full and inner thicknesses of the retina were assessed. Results: There were significant differences in all sectors between the groups in regard to the superficial vessel density and the inner and full thicknesses of the retina. The nasal sector of the macular superficial vessel density was affected more in LHON than in NA-AION; the same with the temporal sector of the retinal thickness. There were no significant differences between the groups in the deep vessel plexus. There were no significant differences between the vasculature of the inferior and superior hemifields of the macula in all groups and no correlation with the visual function. Conclusions: The superficial perfusion and structure of the macula assessed with OCT-A are affected both in chronic LHON and NA-AION, but more in LHON eyes, especially in the nasal and temporal sectors. Full article
(This article belongs to the Special Issue Update on Optical Coherence Tomography Angiography Imaging in Optic Neuropathies)
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