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Special Issue "Advances in Diagnosis and Pathophysiology of Microvascular Dysfunction"
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 10871
Special Issue Editor
Interests: biomechanics; rehabilitation engineering; computational modeling; exercise physiology; signal analysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Microcirculation is the system that brings oxygen and nutrients to local cells and removes metabolic wastes. The study of the structure, function, and adaptation of the microvascular system has played an essential role in understanding cardiovascular diseases. Research studies have shown promise of using the onset and progression of microvascular dysfunction as an indicator and risk determinant of other diseases, including diabetes, cancer, and stroke. Additionally, microvasculature is recognized as one of the most important routes for drug delivering in disease conditions.
Recent advances in computational models and imaging technologies have provided new opportunities to investigate microvascular dysfunction. Under pathophysiological conditions (e.g., diabetes and cancer), structural and functional adaptations of microvascular networks can be quantified using novel imaging technologies and advanced quantification metrics, such as multispectral and hyperspectral imaging, optical coherence tomography, and laser speckle contrast imaging. The use of wavelet analysis of laser Doppler signals has provided a novel way to diagnose the underlying mechanisms of microvascular dysfunction caused by the endothelial, neurogenic, and myogenic controls. The complexity analysis of microvascular blood flow reveals pathophysiological conditions that cannot be assessed through traditional methods.
The objective of this Special Issue is to bring together researchers from various fields to better understand the role of microvascular dysfunction in the development of diseases using advanced computational dynamics, novel imaging technologies, and theoretical models. This Special Issue also welcomes the applications of these novel methods and technologies in various clinical patients for early diagnosis of microvascular dysfunction and better understanding of the role of microvascular dysfunction in progression of various diseases. All topics related to the recent advances in diagnosis and pathophysiology of microvascular dysfunction are welcome.
Dr. Yih-Kuen Jan
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Blood flow regulation
- Microvascular dynamics
- Microvascular assessments of an organ (e.g., skin, heart, and msucle)
- Microvascular network modeling
- Microvascular physiology
- Microvasuclar remodeling