Special Issue "Dental Peri-Implant Point-of-Care Tests"
Deadline for manuscript submissions: 28 February 2021.
Interests: matrix metalloproteinase (MMP-8) and related factors; synthetic MMP-inhibitors; periodontal research; chair-side/bed-side/point-of-care MMP-diagnostic tests in periodontitis and related systemic diseases
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Currently, the diagnosis of both periodontal and peri-implant diseases is mainly based on the clinical measurement of pocket depths, attachment loss, and bleeding on probing, together with radiographic examination. These diagnostic procedures can assess only past tissue destruction and do not provide any information about the current disease states and activities or future risk of progression. Therefore, the need for potential biomarkers emerges in order to screen the susceptible sites and patients in order to intervene in a timely manner and prevent irreversible periodontal and dental peri-implant tissue destruction in both periodontitis and dental peri-implantitis.
Point-of-care tests are simple medical tests that can be performed at the bedside. Point-of-care tests are often accomplished through the use of transportable, portable, and handheld instruments. Cheaper, faster, and smarter point-of-care tests devices have increased the use of Point-of-care tests approaches by making it cost-effective for many diseases. Additionally, it is very desirable to measure various analytes simultaneously in the same specimen, allowing rapid, low-cost, and reliable quantification. Therefore, Point-of-care testing has become more important for medical diagnostics in the last decade. In this context, and in view of the latest advances in translational research on periodontal and peri-implant disease biomarkers, point-of-care technologies are emerging as new tools to target periodontitis and peri-implantitis. In particular, these technologies could help to pinpoint the crucial transition of gingivitis or subclinical periodontitis without clinical or radiographic manifestations to active periodontal disease, with progressive deepened pockets and attachment loss.
Prof. Dr. Timo Sorsa
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