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Advances in Diagnosis and Treatment of Digestive Disease Using Endoscopic...
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Advances in Diagnosis and Treatment of Digestive Disease Using Endoscopic Imagine and Endoscopic Ultrasound

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 8436

Special Issue Editor

Dr. Zhendong Jin

E-Mail Website
Guest Editor
The First Affiliated Hospital of Naval Medical University, Shanghai, China
Interests: endoscopic diagnosis and treatment; endoscopic ultrasound; cancer imaging; medical ultrasound

Special Issue Information

Dear Colleagues,

Modern medical technology is mainly based on the concept of minimally invasive medicine, and endoscopy is an important representative of minimally invasive medical technology. At present, digestive endoscopy technology has been comprehensively and maturely developed, and is the main method for the diagnosis and treatment of digestive system diseases. Meanwhile, endoscopic ultrasound, a novel technology combining endoscopy and ultrasound imaging, has shown its advantage in the diagnosis and treatment of digestive disease, including endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for diagnosis and EUS-guided biliary drainage (EUS-BD) and EUS-guided gallbladder drainage(EUS-GBD) for treatment. This Special Issue invites the submission of both original and review papers, aiming to collect new findings in the diagnosis and treatment of digestive disease using endoscopic images and endoscopic ultrasound.

Dr. Zhendong Jin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endoscopic ultrasound
  • endoscopic imaging
  • endoscopic ultrasound-guided fine needle aspiration
  • endoscopic ultrasound-guided fine needle biopsy
  • interventional endoscopic ultrasound
 

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Published Papers (5 papers)

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Research

Jump to: Review

10 pages, 544 KiB  
Article
Lumen-Apposing Metal Stents in the Management of Complex Pelvic Abscesses
by Kenneth W. Chow, Nicholas A. Cumpian, Ranjit Makar, Pejman Zargar, Fouzia Oza, Idrees Suliman, Viktor Eysselein and Sofiya Reicher
Diagnostics 2024, 14(24), 2854; https://doi.org/10.3390/diagnostics14242854 - 18 Dec 2024
Viewed by 679
Abstract
Background: Lumen-apposing metal stents (LAMS) are utilized in a wide range of therapeutic gastrointestinal applications. We present our experience with LAMS-assisted drainage of complex pelvic abscesses at a large safety-net hospital. Methods: EUS-guided LAMS placements for pelvic abscesses from July 2020 to June [...] Read more.
Background: Lumen-apposing metal stents (LAMS) are utilized in a wide range of therapeutic gastrointestinal applications. We present our experience with LAMS-assisted drainage of complex pelvic abscesses at a large safety-net hospital. Methods: EUS-guided LAMS placements for pelvic abscesses from July 2020 to June 2024 were analyzed. Data were collected on patient demographics, procedure indications, fluid collection size, stent characteristics, stent dwell time, and complications. All cases underwent multidisciplinary review with Surgery and Interventional Radiology (IR) prior to LAMS-assisted drainage; all were deemed not amenable to drainage by IR. Results: Eleven patients underwent EUS-guided drainage of complex pelvic abscesses with cautery-enhanced LAMS. Diverticulitis was the most common cause of abscesses (n = 6; 55%). The average time from presentation to drainage was 7 days (1–18). The average abscess size was 7.2 cm (3.9–12.0 cm). The most common LAMS size was 15 mm × 10 mm; each was placed through the left colon and rectum with both technical and clinical success. All abscesses completely resolved with a mean stent dwell time of 28 days (17–42 days). After stent removal, the fistula was not routinely closed. No complications such as stent migration, bleeding, or perforation occurred. There were no recurrences and no patients required additional surgical or IR procedures with a mean follow-up of 25 weeks (SD 35.6). Conclusions: Adequate drainage is the cornerstone of pelvic abscess management, but IR or surgical access can be challenging, with inadequate drainage and prolonged hospitalization leading to significant morbidity. In our experience, EUS-guided, LAMS-assisted drainage provides a safe and effective alternative for managing pelvic abscesses. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Treatment of Digestive Disease Using Endoscopic Imagine and Endoscopic Ultrasound)
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12 pages, 2272 KiB  
Article
Differential Diagnosis of Solid Pancreatic Lesions Using Detective Flow Imaging Endoscopic Ultrasonography
by Haruo Miwa, Kazuya Sugimori, Shoichiro Yonei, Hayato Yoshimura, Kazuki Endo, Ritsuko Oishi, Akihiro Funaoka, Hiromi Tsuchiya, Takashi Kaneko, Kazushi Numata and Shin Maeda
Diagnostics 2024, 14(9), 882; https://doi.org/10.3390/diagnostics14090882 - 24 Apr 2024
Cited by 2 | Viewed by 2109
Abstract
The differential diagnosis of solid pancreatic lesions (SPLs) using B-mode endoscopic ultrasonography (EUS) is challenging. Detective flow imaging (DFI) offers the potential for detecting low-flow vessels in the pancreas, thus enhancing diagnostic accuracy. This retrospective study aimed to investigate DFI-EUS findings of SPLs [...] Read more.
The differential diagnosis of solid pancreatic lesions (SPLs) using B-mode endoscopic ultrasonography (EUS) is challenging. Detective flow imaging (DFI) offers the potential for detecting low-flow vessels in the pancreas, thus enhancing diagnostic accuracy. This retrospective study aimed to investigate DFI-EUS findings of SPLs and analyze their differential diagnostic accuracy for pancreatic cancer. We included 104 patients with pathologically confirmed SPLs who underwent EUS between April 2021 and June 2023. Expert endosonographers, blinded to the patients’ clinical data, evaluated images obtained through B-mode, eFLOW, and DFI-EUS. The frame rate and vessel detection sensitivity were compared between eFLOW and DFI, and the diagnostic criteria for pancreatic cancer were established. The visualization rate for vessels in SPLs was significantly higher with DFI-EUS (96%) compared to eFLOW (27%). Additionally, DFI showed a superior frame rate, sensitivity (99%), and accuracy (88%) for detecting pancreatic cancer, although with a modest specificity (43%). On DFI-EUS, characteristics such as hypovascularity, peritumoral vessel distribution, or spotty vessel form were suggestive of pancreatic cancer. DFI-EUS significantly improved the visualization of vascular structures within the SPLs, highlighting its efficacy as a diagnostic modality for pancreatic cancer. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Treatment of Digestive Disease Using Endoscopic Imagine and Endoscopic Ultrasound)
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11 pages, 1486 KiB  
Article
Novel Technique of Endoscopic Ultrasonography for the Differential Diagnosis of Gallbladder Lesions and Intraductal Papillary Mucinous Neoplasms: A Single-Center Prospective Study
by Yasunobu Yamashita, Reiko Ashida, Takaaki Tamura, Toshio Shimokawa, Hirofumi Yamazaki, Yuki Kawaji, Takashi Tamura, Keiichi Hatamaru, Masahiro Itonaga and Masayuki Kitano
Diagnostics 2023, 13(13), 2132; https://doi.org/10.3390/diagnostics13132132 - 21 Jun 2023
Cited by 8 | Viewed by 1696
Abstract
Detective flow imaging endoscopic ultrasonography (DFI-EUS) is an innovative imaging modality that was developed to detect fine vessels and low-velocity blood flow without contrast agents. We evaluate its utility for the differential diagnosis of gallbladder lesions and intraductal papillary mucinous neoplasms (IPMNs). We [...] Read more.
Detective flow imaging endoscopic ultrasonography (DFI-EUS) is an innovative imaging modality that was developed to detect fine vessels and low-velocity blood flow without contrast agents. We evaluate its utility for the differential diagnosis of gallbladder lesions and intraductal papillary mucinous neoplasms (IPMNs). We enrolled patients who underwent DFI-EUS, e-FLOW EUS, and contrast-enhanced EUS for gallbladder lesions or IPMNs. The detection of vessels using DFI-EUS and e-FLOW EUS was compared with that via contrast-enhanced EUS and pathological findings. The vessel pattern was also categorized as regular or irregular. Of the 33 lesions included, there were final diagnoses of 13 IPMNs and 20 gallbladder lesions. DFI-EUS was significantly superior to e-FLOW EUS for discriminating between mural nodules and mucous clots and between solid gallbladder lesions and sludge using the presence or absence of vessel detection in lesions (p = 0.005). An irregular vessel pattern with DFI-EUS was a significant predictor of malignant gallbladder lesions (p = 0.002). DFI-EUS is more sensitive than e-FLOW-EUS for vessel detection and the differential diagnosis of gallbladder lesions and IPMNs. Vessel evaluation using DFI-EUS may be a useful and simple method for differentiating between mural nodules and mucous clots in IPMN, between solid gallbladder lesions and sludge, and between malignant and benign gallbladder lesions. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Treatment of Digestive Disease Using Endoscopic Imagine and Endoscopic Ultrasound)
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Review

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11 pages, 883 KiB  
Review
The Role of Endoscopic Ultrasound-Guided Shear Wave Elastography in Pancreatic Diseases
by Yazan Abboud and Srinivas Gaddam
Diagnostics 2024, 14(20), 2329; https://doi.org/10.3390/diagnostics14202329 - 19 Oct 2024
Viewed by 1465
Abstract
Elastography is a non-invasive imaging modality that has been developed for the evaluation of the stiffness of various organs. It is categorized into two main types: strain elastography and shear wave elastography. While strain elastography offers valuable information on the mechanical properties of [...] Read more.
Elastography is a non-invasive imaging modality that has been developed for the evaluation of the stiffness of various organs. It is categorized into two main types: strain elastography and shear wave elastography. While strain elastography offers valuable information on the mechanical properties of the organ being studied, it is limited by the qualitative nature of its measurements and its reliance on operator skills. On the other hand, shear wave elastography overcomes these limitations as it provides a quantitative assessment of tissue stiffness, offers more reproducibility, and is less operator-dependent. Endoscopic ultrasound-guided shear wave elastography (EUS-SWE) is an emerging technique that overcomes the limitations of transabdominal ultrasound in the evaluation of the pancreas. A growing body of literature has demonstrated its safety and feasibility in the evaluation of pancreatic parenchyma. This article provides a comprehensive review of the current state of the literature on EUS-SWE, including its technical aspects, clinical applications in the evaluation of various pancreatic conditions, technological limitations, and future directions. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Treatment of Digestive Disease Using Endoscopic Imagine and Endoscopic Ultrasound)
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11 pages, 598 KiB  
Review
Diagnosis by Endoscopic Ultrasonography-Guided Sampling through the Lower Gastrointestinal Tract
by Jingyuan Wang, Yue Liu, Chang Wu, Jiayu Fan, Zhendong Jin and Kaixuan Wang
Diagnostics 2024, 14(1), 64; https://doi.org/10.3390/diagnostics14010064 - 27 Dec 2023
Cited by 1 | Viewed by 1556
Abstract
Endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/FNB) is very safe and has a high diagnostic rate for upper gastrointestinal lesions, especially pancreatic lesions, but its application in the lower gastrointestinal tract has rarely been reported. Due to the tortuous course of the colorectum, with the [...] Read more.
Endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/FNB) is very safe and has a high diagnostic rate for upper gastrointestinal lesions, especially pancreatic lesions, but its application in the lower gastrointestinal tract has rarely been reported. Due to the tortuous course of the colorectum, with the sigmoid colon particularly prone to perforation, most endoscopists are reluctant to perform lateral-sector endoscopic ultrasound scanning without a water-bag protection for the puncture. The ultrasonic endoscopy and flexible puncture needle techniques recently introduced into clinical practice have made ultrasound-guided puncture safer and more convenient. In addition, endoscopists have carefully tested various protective measures to improve the safety of the lower gastrointestinal puncture, substantially increasing its clinical feasibility. In this article, we review the iterations of endoscopic ultrasound equipment introduced in recent years and the many ingenious ideas proposed by endoscopists regarding lower gastrointestinal puncture. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Treatment of Digestive Disease Using Endoscopic Imagine and Endoscopic Ultrasound)
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