Special Issue "Novel Point-of-Care Technologies in Diagnostics 2018"
Deadline for manuscript submissions: closed (22 November 2018)
Dr. Paul K. Drain
Departments of Global Health, Medicine (Infectious Diseases), and Epidemiology, University of Washington, Seattle, USA. Mailing Address: 325 Ninth Ave, UW Box 359927, Seattle, WA 98104, USA
Website | E-Mail
Interests: HIV/AIDS; tuberculosis; point-of-care diagnostics; point-of-care testing; implementation science; global health; resource-limited settings
Point-of-care tests have changed the delivery and impact of medical care by facilitating a migration of diagnostic testing from centralized laboratories to the clinical site of patient care, or even a person’s home. Research and development of point-of-care tests has grown steadily over the last 20 years, and the global point-of-care diagnostic market is expected to surpass US $30 billion in the year 2020. Point-of-care tests have been developed for use in all medical settings, a wide variety of medical specialties and subspecialties, and for both infectious and non-communicable diseases. Novel point-of-care technologies are becoming increasing more sophisticated and complex with lab-on-a-chip capabilities, and the latest generation of point-of-care tests offer rapid analysis of human and pathogen genomic data to accelerate more appropriate and personalized therapies.
Any successful point-of-care technology will require a balancing of accuracy, rapidity, accessibility, and cost. While a fundamental objective is to be diagnostically accurate, point-of-care tests that can be quickly and easily performed by clinical health care workers and at low operational costs will be the most successful. The largest potential impact will be in resource-limited settings, where expensive laboratory infrastructure is either inaccessible or completely unavailable. However, several studies of point-of-care tests have demonstrated only minimal impact on the burden of disease in resource-limited settings, suggesting their incorporation in health systems has either been incomplete or poorly implemented.
Although centralized reference laboratories will maintain a critical role in providing confirmatory diagnosis, future healthcare delivery is likely to be more reliant on point-of-care technologies. In this Special Issue of Diagnostics, we welcome submission of articles that showcase novel point-of-care technologies in diagnostics. An article may demonstrate sophisticated laboratory technologies that are pushing technological boundaries, clinical implementation solutions that balance the complexity and accessibility of novel technologies, or modeling studies that provide information on future strategies to safely use point-of-care technologies for maximal benefit. The success of point-of-care technologies will depend on demonstrating diagnostic accuracy and clinical value for the benefit of individuals and the health of communities.
Dr. Paul K. Drain
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 850 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- point-of-care test
- diagnostic testing
- nucleic acid amplification
- resource-limited settings