Diagnosis in Obstetrics and Gynecology

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (28 February 2023) | Viewed by 2448

Special Issue Editor


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Guest Editor
Second Department of Obstetrics and Gynecology, School of Medicine, Aristotle University of Thessaloniki, “Ippokrateion” Hospital, 54642 Thessaloniki, Greece
Interests: imaging; fetal; obstetrics; ultrasound; gynecological oncology; markers; genetics; screening; cancer

Special Issue Information

Dear Colleagues, 

The field of diagnosis in obstetrics and gynecology has seen significant progress in recent years, including advances in equipment, the emergence of new biochemical and biophysical markers, adoption of new genetic tests, development of new screening algorithms, and even advances in methodology and diagnostic ethics. The aim of this Special Issue is to collect in one place research articles that illustrate and describe this progress in a field as wide as modern obstetrics and gynecology. In this context, we welcome original research and meta-analysis articles covering aspects of all diagnostic modalities (e.g., imaging, markers, genetics) in all fields of obstetrics and gynecology, including fetal and perinatal medicine, gynecological oncology, reproductive medicine and urogynecology.

Dr. Alexandros Sotiriadis
Guest Editor

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Keywords

  • imaging
  • fetal
  • obstetrics
  • ultrasound
  • gynecological oncology
  • markers
  • genetics
  • screening
  • cancer

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Published Papers (1 paper)

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11 pages, 2479 KiB  
Systematic Review
Clinical Characteristics, Treatment, and Outcomes of Peritoneal Strumosis: A Report of Three Cases and Systematic Review
by Sijian Li, Xiaoxue Wang, Ruping Hong, Xinyue Zhang, Min Yin, Tianyu Zhang and Jiaxin Yang
Diagnostics 2023, 13(9), 1581; https://doi.org/10.3390/diagnostics13091581 - 28 Apr 2023
Cited by 5 | Viewed by 1987
Abstract
Benign struma ovarii (SO) has a probability of metastasis named “peritoneal strumosis”, which is extremely rare, such that the specific clinical characteristics, treatment options, and survival outcomes remain unclear. We screened three cases of peritoneal strumosis among 229 cases of SO treated in [...] Read more.
Benign struma ovarii (SO) has a probability of metastasis named “peritoneal strumosis”, which is extremely rare, such that the specific clinical characteristics, treatment options, and survival outcomes remain unclear. We screened three cases of peritoneal strumosis among 229 cases of SO treated in our hospital. Case 1 was a 36-year-old woman with extensive peritoneal seedings at initial presentation. The second one was a 49-year-old with trocar site implant 11 years after laparoscopic adnexectomy. Case 3 was a 45-year-old woman who had an isolated lesion at the anterior surface of the rectum after laparoscopic ovarian cystectomy for SO 14 years ago. These three patients underwent surgery without any adjuvant treatment and remained disease-free after 30 to 68 months. A systematic review was then conducted and another 16 cases were identified. More than half (10/19, 52.6%) of the patients had previous SO-related ovarian surgery. The median interval between prior SO-related surgery and the initial presentation of peritoneal strumosis was 10.0 years; both regional and distant metastasis, even in the liver, lung, and heart, could also be affected. Surgery was the mainstay therapy (18/19, 94.7%), in which six patients (6/19, 31.7%) were treated with total thyroidectomy (TT) followed by radioiodine (RAI) therapy. Postoperative chemotherapy was only applied in one patient, and the last one only received a diagnostic biopsy without further treatment. Recurrence was noted in two patients with a median recurrence-free survival of 12 years, where surgical excision and RAI were then performed. No death occurred after a mean follow-up of 53 months, where 12 patients achieved no evidence of disease and five were alive with the disease. Peritoneal strumosis has unpredictable biological behaviors and the crude incidence is approximately 1.3% in SO. Patients with peritoneal strumosis have excellent survival outcomes, irrespective of different treatment strategies employed. Surgery with personalized RAI should be preferred and long-term close monitoring is recommended. Full article
(This article belongs to the Special Issue Diagnosis in Obstetrics and Gynecology)
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