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Diagnostics
Special Issues
Future Trends in Diagnostic and Interventional Radiology
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Future Trends in Diagnostic and Interventional Radiology

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 2229

Special Issue Editor

Dr. Francesco Giurazza

E-Mail Website
Guest Editor
Department of Vascular and Interventional Radiology, Cardarelli Hospital, 80131 Naples, Italy
Interests: application of interventional radiology in the fields of emergency; vascular diseases and oncology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recent advancements in diagnostic and interventional radiology have significantly enhanced medical imaging precision and expanded therapeutic capabilities through innovations in advanced imaging modalities and minimally invasive techniques, leading to reduced invasiveness and recovery time. These developments enable earlier disease detection, personalized treatment planning, and improved patient outcomes across diverse clinical settings.

This Special Issue aims to serve as a platform for researchers, clinicians, and engineers to share cutting-edge findings in image-guided diagnostics and interventions. It particularly encourages submissions from authors exploring clinical impact of interventional radiology procedures, AI-driven imaging analytics, novel interventional devices, and translational research bridging radiology with oncology, neurology, cardiovascular sciences, and emerging fields like radiomics. By emphasizing rigor and innovation, this Special Issue seeks to advance patient care through multidisciplinary collaboration and technology dissemination.

We look forward to your submissions.

Dr. Francesco Giurazza
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diagnostic radiology
  • interventional radiology
  • medical imaging
  • artificial intelligence
  • minimally invasive therapy
  • radiomics
  • precision medicine
  • multidisciplinary research

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

13 pages, 998 KB  
Article
Balloon-Occluded Hepatic Radioembolization with Yttrium-90 (b-TARE) in Selected Patients with Unresectable Heterogeneous Hepatocellular Carcinoma (HCC): A Safe and Effective Approach to Improve the Dose Rate
by Leonardo Teodoli, Nicolò Ubaldi, Claudio Trobiani, Federico Cappelli, Sara Ungania, Pierleone Lucatelli, Rosa Sciuto and Giulio Vallati
Diagnostics 2025, 15(24), 3237; https://doi.org/10.3390/diagnostics15243237 - 18 Dec 2025
Viewed by 107
Abstract
Background/Objectives: To evaluate the efficacy of balloon occlusion trans-arterial hepatic radioembolization with Yttrium-90 (b-TARE) in optimizing dose activity in patients with large or multifocal Hepatocellular Carcinoma (HCC) lesions with heterogeneous macroaggregate distribution by retrospectively comparing outcomes with a similar cohort treated with standard [...] Read more.
Background/Objectives: To evaluate the efficacy of balloon occlusion trans-arterial hepatic radioembolization with Yttrium-90 (b-TARE) in optimizing dose activity in patients with large or multifocal Hepatocellular Carcinoma (HCC) lesions with heterogeneous macroaggregate distribution by retrospectively comparing outcomes with a similar cohort treated with standard TARE. Methods: This single-center restrospective study included sixty-three consecutive patients with unresectable HCC treated with TARE, of whom 24/63 had balloon-occluded TARE and 39/63 had standard TARE. Both cohorts included large or multifocal HCC lesions characterized by heterogeneous macroaggregate distribution, also in relation to the angiosome framework. The impact of b-TARE was analyzed using 2D and 3D dosimetry with dedicated software on post-procedural SPECT-CT. Dosimetric b-TARE results were retrospectively compared with standard TARE. Results: Both 2D and 3D SPECT-CT analyses demonstrated a better dosimetry profile in the b-TARE group. Concerning 2D evaluation, the activity intensity peak was significantly higher in the b-TARE group compared to the TARE group (998.6 ± 394.9 vs. 578.8 ± 313.3, p = 0.004). Regarding 3D dose analysis, the mean intra-lesion dose administered was significantly higher in the b-TARE group (162.7 ± 54.3 Gy vs. 111.2 ± 44.5 Gy, p = 0.01). There was no increase in significant complications or in the mean dose delivered to the normal liver in the b-TARE group. Conclusions: The employment of balloon occlusion in TARE was associated with a higher activity intensity peak and lesion absorbed dose on voxel-based dosimetry, compared to standard TARE, in patients with heterogeneous HCC and uneven macroaggregate distribution, without increasing mean non-tumoral liver dose. Full article
(This article belongs to the Special Issue Future Trends in Diagnostic and Interventional Radiology)
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10 pages, 225 KB  
Article
Interventional Radiology Management of Renal Artery Stenosis After Kidney Transplant: Single-Center Experience and Management Strategies
by Ahmad Mirza, Munazza Khan, Usman Baig, Shameem Beigh and Imran Gani
Diagnostics 2025, 15(13), 1592; https://doi.org/10.3390/diagnostics15131592 - 23 Jun 2025
Viewed by 1674
Abstract
Background/Objectives: The course of treatment for renal artery stenosis following renal transplantation depends on the severity of the condition. Mild cases are typically managed medically, while more significant stenosis with flow limitation and graft dysfunction requires percutaneous intervention. Surgical treatment is generally reserved [...] Read more.
Background/Objectives: The course of treatment for renal artery stenosis following renal transplantation depends on the severity of the condition. Mild cases are typically managed medically, while more significant stenosis with flow limitation and graft dysfunction requires percutaneous intervention. Surgical treatment is generally reserved as a last resort. This study aimed to evaluate the outcomes of interventional radiology in managing renal artery stenosis at our transplant center. Methods: The electronic medical records of patients who underwent renal transplantation at our center between January 2020 and December 2024 were reviewed to identify cases of renal artery stenosis and their subsequent management through interventional radiology. Sociodemographic and clinical data were collected for both recipients and donors. Data analysis was performed using SPSS version 26. Results: Out of the total 368 patients who received renal allograft at our center from January 2020 to December 2024, 25 patients were confirmed with duplex ultrasound to have renal artery stenosis. The majority of affected patients were African American, had Class I Obesity and presented with cardiovascular co-morbidities. The mean time from transplant to the diagnosis of RAS was 4.25 (SD ± 3.81) months. The mean serum creatinine level at presentation was 2.54 (SD ± 1.21 mg/dL). All 25 patients underwent digital subtraction angiography, and 24 patients were confirmed to have renal artery stenosis requiring further intervention. The creatinine levels at one week, three months and one year post-intervention were 2.12 (SD ± 1.00), 1.83 (SD ± 0.63) and 2.15 (SD ± 1.68) mg/dL, respectively. Conclusions: Percutaneous interventional treatment for renal artery stenosis is associated with improvements in hemodynamic parameters and the stabilization of allograft function. Follow-up is needed to monitor for the potential occurrence of restenosis. Full article
(This article belongs to the Special Issue Future Trends in Diagnostic and Interventional Radiology)
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