Recent Advances in the Development of Sustainable Cosmetic Products With Nanotechnology

A special issue of Cosmetics (ISSN 2079-9284). This special issue belongs to the section "Cosmetic Technology".

Deadline for manuscript submissions: closed (31 December 2025) | Viewed by 2606

Special Issue Editor


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Guest Editor
Departamento de Fármacos e Medicamentos, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro (UFRJ), Cidade Universitária, Ilha do Fundão, Rio de Janeiro 21941-902, RJ, Brazil
Interests: nanotechnology; microtechnology; neglected diseases; modified release; nanoparticles; nanoemulsions; liposomes
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Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to our next Special Issue on the “Recent Advances in the Development of Sustainable Cosmetic Products with Nanotechnology”. This Special Issue aims to highlight the most recent advances in the application of nanotechnology in the areas of sustainable cosmetic products, involving the development of biodegradable nanocarriers made from natural and biocompatible polymers that reduce the environmental impact of cosmetics; the encapsulation of natural ingredients (such as essential oils and plant extracts), and improving their stability, efficacy, and skin permeation; sustainable nanomaterials such as nanocellulose use, green nanochemistry, and nanoparticles derived from renewable sources; waste reduction through nano-structured systems that allow for the encapsulation of ingredients from waste; green nanotechnology and green synthesis methods, such as solvent-free processes and biosynthesis-based nanoparticle production; nanotechnological UV filters advancing the development of zinc oxide and titanium dioxide nanoparticles to enhance UV protection without harming the environment. Areas of research may include the following:

  • Biodegradable nanocarriers made from natural and biocompatible polymers that reduce the environmental impact of cosmetics.
  • The encapsulation of natural ingredients (such as essential oils and plant extracts), improving their stability, efficacy, and skin permeation.
  • Sustainable nanomaterials such as the use of nanocellulose, lipid nanoparticles, liposomes, green nanochemistry, and nanoparticles derived from renewable sources.
  • Waste Reduction through nano-structured systems that allow for the encapsulation of ingredients from waste.
  • Green Nanotechnology through green synthesis methods, such as solvent-free processes and biosynthesis-based nanoparticle production.
  • Nanotechnology for photoprotectors and cosmetics actives: design, characterization, in vitro release, and ex vivo permeation with artificial skin.

Prof. Dr. Eduardo Ricci Junior
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cosmetics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanotechnology
  • sustainable
  • cosmetic
  • nanochemistry
  • nanoparticles

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Published Papers (2 papers)

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Research

24 pages, 7556 KB  
Article
Post-Electrospinning Surface Functionalization of PCL Nanofibrous Membranes with Sisal Extracts: Extract-Dependent Cytocompatibility and Bioactivity
by Felipe Romici Zane Lordelo Nogueira, Julia Amanda Rodrigues Fracasso, Luisa Taynara Silvério da Costa, Wellington Ricardo Pereira Martins, Amanda Letícia Santos Costa, Ligia Maria Manzine Costa and Lucinéia dos Santos
Cosmetics 2026, 13(2), 80; https://doi.org/10.3390/cosmetics13020080 - 23 Mar 2026
Viewed by 635
Abstract
Chronic wounds are frequently associated with persistent inflammation, motivating the development of biofunctional materials capable of modulating cellular responses. In this proof-of-concept study, electrospun poly(ε-caprolactone) (PCL) nanomembranes were surface-functionalized by post-electrospinning drop coating with extracts derived from Agave sisalana agroindustrial residue obtained through [...] Read more.
Chronic wounds are frequently associated with persistent inflammation, motivating the development of biofunctional materials capable of modulating cellular responses. In this proof-of-concept study, electrospun poly(ε-caprolactone) (PCL) nanomembranes were surface-functionalized by post-electrospinning drop coating with extracts derived from Agave sisalana agroindustrial residue obtained through two distinct routes: a saponin-rich fraction (EDP) and an acid-hydrolyzed sapogenin-enriched fraction (EAH). The study aimed to investigate how the extract phytochemical profile influences cytocompatibility and bioactivity when incorporated onto electrospun platforms. Phytochemical analysis revealed high total saponin content in EDP (33.83 ± 2.93 g/100 g) and significant sapogenin content in EAH (11.56 ± 0.60 g/100 g). SEM and FTIR-ATR analyses confirmed preservation of the fibrous architecture and polymer backbone, indicating predominantly physical surface incorporation. Biological evaluation demonstrated extract-dependent responses: PCL+EDP 5% exhibited marked cytotoxicity, consistent with the known membrane-disruptive properties of glycosylated saponins, whereas PCL+EAH 5% maintained high cell viability and showed anti-inflammatory activity (75% inhibition of phagocytosis; 56% protection against hemolysis) along with enhanced fibroblast migration (100% wound closure at 72 h). These findings highlight the critical role of extract chemical composition in determining the biological performance of surface-functionalized nanofibrous systems and support sapogenin-enriched fractions as safer bioactive modifiers for electrospun biomaterial platforms. Full article
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26 pages, 2469 KB  
Article
Development of a Multifunctional Phytocosmetic Nanoemulsion Containing Achillea millefolium: A Sustainable Approach
by Thais Silva Christiani, Luciana Pereira Rangel, Andressa Souto Ramalho Soares, Anne Caroline Candido Gomes, Ariely Costa dos Santos, Mariana Sato S. B. Monteiro, Naomi Kato Simas and Eduardo Ricci-Junior
Cosmetics 2025, 12(6), 255; https://doi.org/10.3390/cosmetics12060255 - 11 Nov 2025
Cited by 1 | Viewed by 1554
Abstract
Skin aging, including photoaging, is primarily triggered by chronic exposure to solar radiation, which induces free radical formation, cellular deoxyribonucleic acid (DNA) damage, and structural skin alterations. Achillea millefolium L. (Asteraceae) is rich in phenolic compounds and alkamides, substances known for their antioxidant [...] Read more.
Skin aging, including photoaging, is primarily triggered by chronic exposure to solar radiation, which induces free radical formation, cellular deoxyribonucleic acid (DNA) damage, and structural skin alterations. Achillea millefolium L. (Asteraceae) is rich in phenolic compounds and alkamides, substances known for their antioxidant activity. This study aimed to develop and characterize a photoprotective phytocosmetic nanoemulsion containing crude root extract of A. millefolium. The extract exhibited a total phenolic content of 3.067 ± 1.911 µg GAE/mL, potent antioxidant activity (EC50 = 69.11 ± 8.899 µg/mL), moderate tyrosinase inhibition (19 ± 1.8%), and no cytotoxicity in keratinocytes. The extract was incorporated into nanoemulsions at concentrations of 0.1%, 0.5%, and 1%. The resulting droplets showed mean diameters of 217 to 230 nm, with a significant increase in the polydispersity index (PDI) after extract addition (p < 0.05). Transmission electron microscopy (TEM) confirmed the spherical morphology of the droplets. The in vitro sun protection factor (SPF) was 14 ± 0.9 in the control formulation and increased to 15 ± 2.0 (0.1%), 22 ± 5.2 (0.5%), and 17 ± 1.0 (1%), suggesting a synergistic effect between the extract and chemical filters. All formulations demonstrated UVA/UVB ratio > 0.6, a pH near to 5, occlusive properties, and good spreadability. The results indicate that A. millefolium extract holds potential for safe photoprotective formulations, offering a valuable antioxidant and depigmenting activity in addition to enhancing the SPF. This position is an innovative alternative to phytocosmetic development. Full article
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