Angiogenesis in Diseases: Molecular Mechanism and Regulation

Dear Colleagues,

Angiogenesis is the physiological process of forming new capillaries from existing vasculature and is a key process involved in embryonic development as well as in organ growth and repair. Excessive angiogenesis is directly or indirectly associated with many diseases, including cancer, autoimmune diseases, diabetic retinopathy, rheumatoid arthritis and atherosclerosis. Conversely, insufficient vascularization and insufficient vessel growth can exacerbate or lead to cerebral ischemia, coronary heart disease, and delayed wound healing. In cancer, the relationship between endoglin and tumor angiogenesis has been extensively studied. Anti-angiogenic drugs have been intensively investigated for the treatment of cancer; however, these are ineffective in some cases and often develop resistance.

This Special Issue aims to summarize the current knowledge and cutting-edge research on the molecular mechanisms of angiogenesis. We look forward to receiving valuable contributions from researchers and academics all around the world.

Prof. Dr. Alicia Rodríguez-Barbero
Guest Editor

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• blood vessels
• angiogenic factors
• trophic factors
• angiogenesis biomarkers
• cancers
• heart diseases