Advances in Molecular Therapies and Disease Associations in Diabetes
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 214
Special Issue Editors
Interests: bioinformatics; genetic network analysis; biomarker discovery; data integration; machine learning in biomedical research; systems biology; drug development; medical image analysis; neurodegenerative diseases; statistical modeling
Interests: bioinformatics; mental disorders; next-generation sequencing; machine learning; protein structure modeling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Diabetes mellitus is a multifaceted metabolic disorder characterized by chronic hyperglycemia due to defects in insulin secretion, action, or both. Beyond its primary impact on glucose metabolism, diabetes significantly influences various physiological systems, increasing the risk of comorbid conditions such as cardiovascular diseases, neurodegenerative disorders, certain cancers, and autoimmune diseases. Understanding these molecular interconnections is crucial for developing targeted therapeutic strategies.
This Special Issue seeks to highlight recent advancements in molecular therapies for diabetes management and elucidate the complex interplay between diabetes and related diseases at the molecular level. We welcome original research articles and comprehensive reviews that delve into the following topics:
- Molecular Mechanisms: Studies exploring pathways linking diabetes to other diseases, including inflammatory processes, endoplasmic reticulum stress, and mitochondrial dysfunction;
- Therapeutic Targets: Identification and validation of novel molecular targets for therapeutic intervention, such as glucose-sensitive insulin analogs which adjust activity based on blood glucose levels, thereby reducing hypoglycemia risk;
- Drug Development: Innovative therapeutic approaches, including the design of multi-receptor agonists which simultaneously activate multiple peptide hormone receptors to enhance efficacy in treating obesity and type 2 diabetes;
- Multi-Omics Approaches: Integration of genomics, proteomics, metabolomics, and system biology to uncover biomarkers and pathways pertinent to diabetes and its comorbidities.
Dr. Hongbao Cao
Dr. Shaolei Teng
Guest Editors
Manuscript Submission Information
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Keywords
- diabetes
- molecular therapies
- comorbidities
- genomics
- proteomics
- metabolomics
- multi-omics
- precision medicine
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