Reviews on Current Advances in Child Neurology Update

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Child Neurology".

Deadline for manuscript submissions: closed (1 June 2024) | Viewed by 4152

Special Issue Editors


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Guest Editor
Departments of Child Health and Neurology, University of Missouri, 400 Keene Street, Columbia, MI 65201, USA
Interests: children’s health; pediatric sleep medicine; pediatric epilepsy; biomedical engineering
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Child Health and the Child Health Research Institute, The University of Missouri School of Medicine, Columbia, MO 65212, USA
Interests: sleep disorder breathing on brain development

Special Issue Information

Dear Colleagues,

Comprehensive up-to-date reviews are sought from experts in the field on topics on current practice and emergent treatments in pediatric neurology. We look forward to receiving your contribution to this Special Issue, which will provide valuable insights into all aspects of current trends in child neurology.

Prof. Dr. Paul R. Carney
Dr. Leila Kheirandish-Gozal
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • epilepsy
  • autism
  • neurogenetics
  • neuroimaging
  • sleep
  • neuromuscular
  • congenital brain disorders
  • trauma
  • movement disorders
  • cerebral palsy

Published Papers (2 papers)

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14 pages, 1083 KiB  
Review
Behavior Rating Inventory of Executive Function in Preschool (BRIEF-P) and Attention-Deficit and Hyperactivity Disorders (ADHD): A Systematic Review and Meta-Analysis of Floor and Ceiling Effects
by Esperanza Bausela-Herreras, Yurena Alonso-Esteban and Francisco Alcantud-Marín
Children 2024, 11(1), 58; https://doi.org/10.3390/children11010058 - 30 Dec 2023
Cited by 1 | Viewed by 1795
Abstract
Background. ADHD is a neurodevelopmental disorder that is accompanied by executive challenges. Objectives. To obtain evidence of the usefulness of the BRIEF-P and to analyze the possible ceiling and floor effect of its scores in the assessment of executive function in preschoolers with [...] Read more.
Background. ADHD is a neurodevelopmental disorder that is accompanied by executive challenges. Objectives. To obtain evidence of the usefulness of the BRIEF-P and to analyze the possible ceiling and floor effect of its scores in the assessment of executive function in preschoolers with signs compatible with a possible diagnosis of ADHD. Method. A search was performed in Science Direct, NCBI (PubMed), and ProQuest Education Journals during the period 2012–2022. We included studies that evaluated samples of individuals with symptomatology compatible with ADHD, with an age range between 2 and 6 years, published in English or Spanish. Of a total of 2538 articles, only seven met the inclusion criteria. The risk of bias was assessed using the QUADAS-2 questionnaire. The main variables were age and executive functioning. Conclusions. Executive deficits in early-age individuals with symptoms compatible with ADHD are more extensive than just deficits in working memory. A floor effect has been found in tests associated with hot executive functions and a ceiling effect in cold executive functions. This makes it necessary to use different tests to assess executive performance in preschoolers with ADHD-compatible symptomatology and to design intervention proposals accordingly. The BRIEF-P is an instrument that facilitates obtaining a sensitive and discriminative executive profile, although it should be used in combination with other neuropsychological performance tests. Full article
(This article belongs to the Special Issue Reviews on Current Advances in Child Neurology Update)
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12 pages, 474 KiB  
Brief Report
A Pilot Feasibility Study Assessing the Combined Effects of Early Behavioral Intervention and Propranolol on Autism Spectrum Disorder (ASD)
by Kathy Hirst, Rachel M. Zamzow, Janine P. Stichter and David Q. Beversdorf
Children 2023, 10(10), 1639; https://doi.org/10.3390/children10101639 - 30 Sep 2023
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Abstract
Autism spectrum disorder (ASD), a neurodevelopmental disorder typified by differences in social communication as well as restricted and repetitive behaviors, is often responsive to early behavioral intervention. However, there is limited information on whether such intervention can be augmented with pharmacological approaches. We [...] Read more.
Autism spectrum disorder (ASD), a neurodevelopmental disorder typified by differences in social communication as well as restricted and repetitive behaviors, is often responsive to early behavioral intervention. However, there is limited information on whether such intervention can be augmented with pharmacological approaches. We conducted a double-blinded, placebo-controlled feasibility trial to examine the effects of the β-adrenergic antagonist propranolol combined with early intensive behavioral intervention (EIBI) for children with ASD. Nine participants with ASD, ages three to ten, undergoing EIBI were enrolled and randomized to a 12-week course of propranolol or placebo. Blinded assessments were conducted at baseline, 6 weeks, and 12 weeks. The primary outcome measures focusing on social interaction were the General Social Outcome Measure-2 (GSOM-2) and Social Responsiveness Scale—Second Edition (SRS-2). Five participants completed the 12-week visit. The sample size was insufficient to evaluate the treatment efficacy. However, side effects were infrequent, and participants were largely able to fully participate in the procedures. Conducting a larger clinical trial to investigate propranolol’s effects on core ASD features within the context of behavioral therapy will be beneficial, as this will advance and individualize combined therapeutic approaches to ASD intervention. This initial study helps to understand feasibility constraints on performing such a study. Full article
(This article belongs to the Special Issue Reviews on Current Advances in Child Neurology Update)
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