Growth Hormone Deficiency in Children: Symptoms, Causes, and Treatment

A special issue of Children (ISSN 2227-9067).

Deadline for manuscript submissions: 10 May 2026 | Viewed by 15

Special Issue Editors


E-Mail Website
Guest Editor
Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy
Interests: endocrinology; children; growth hormone deficiency; puberty; thyroid diseases

E-Mail Website
Guest Editor
Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy
Interests: child; pediatrics; autoinflammation; autoinflammatory disorders

Special Issue Information

Dear Colleague,

Growth Hormone Deficiency (GHD) in childhood represents a significant challenge for clinicians and researchers for both diagnosis and treatment. With this email, I am inviting the scientific community and you to deepen our knowledge on GHD by exploring its underlying mechanisms, peculiar clinical pictures, and biomarkers that may define specific subtypes for a special issue of Children, entitled “Growth Hormone Deficiency in Children: Symptoms, Causes, and Treatment”.

All contributions addressing improved diagnostic strategies, such as standardized stimulation tests, IGF-1–based markers, and neuroimaging approaches, are particularly welcome.

A special emphasis will be placed on studies investigating individualized and evidence-based approaches to recombinant human growth hormone therapy, including predictors of treatment response, optimal dosing of therapy, and long-term outcomes.

Furthermore, this issue seeks innovative perspectives on personalized medicine in pediatric endocrinology, aiming to optimize growth, body composition, and metabolic health in children with GHD, while enhancing their overall quality of life.

Dr. Clelia Cipolla
Prof. Dr. Donato Rigante
Guest Editors

Manuscript Submission Information

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Keywords

  • growth hormone deficiency
  • recombinant human growth hormone
  • diagnosis and biomarkers of growth hormone deficiency
  • predictors of treatment response to human growth hormone
  • personalized medicine

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Published Papers

This special issue is now open for submission.
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