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Children
Special Issues
Pediatric Radiologic Imaging: The Current Status and Further Prospects
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Pediatric Radiologic Imaging: The Current Status and Further Prospects

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Global Pediatric Health".

Deadline for manuscript submissions: closed (25 February 2025) | Viewed by 2024

Special Issue Editor

Dr. Domen Plut

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Guest Editor
Clinical Institute of Radiology, University Medical Centre Ljubljana, Zaloska Cesta 7, 1000 Ljubljana, Slovenia
Interests: children; diagnostic imaging; pediatric radiology; radiography; ultrasound; magnetic resonance imaging; computed tomography
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Diagnostic medical imaging is an integral part of modern medicine and is being performed increasingly. Some of the imaging methods present potential risks for patients, such as ionizing radiation or the need for general anesthesia, and should be used with great care. This is especially important in pediatric radiology due to children’s greater sensitivity to these risks. It is our responsibility to constantly improve the quality and safety of imaging methods and choose optimal modalities for each patient.

Thus, in this Special Issue, we present the current status and future prospects of pediatric radiologic imaging. Pursuing this aim, this Special Issue will include manuscripts focused on diagnostic imaging in children and pediatric radiology. Authors are invited to submit original research (empirical, quantitative, or qualitative) manuscripts, as well as systematic reviews or meta-analyses.

Dr. Domen Plut
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • children
  • diagnostic imaging
  • pediatric radiology
  • radiography
  • ultrasound
  • magnetic resonance imaging
  • computed tomography

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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11 pages, 523 KiB  
Article
Arterial Stiffness and Subclinical Inflammation in Children with Familial Mediterranean Fever: A Comprehensive Analysis
by Nadide Melike Sav, Hasan Baki Altinsoy, Betul Turen and Ayşe Gökçe
Children 2025, 12(2), 232; https://doi.org/10.3390/children12020232 - 14 Feb 2025
Viewed by 522
Abstract
Background/Objectives: Familial Mediterranean fever (FMF) is a chronic autoinflammatory disease. Throughout the disease, subclinical inflammation persists into the remission period. It is known that chronic inflammation causes endothelial dysfunction and, as a consequence, arterial stiffness occurs. In this study, carotid and aortic [...] Read more.
Background/Objectives: Familial Mediterranean fever (FMF) is a chronic autoinflammatory disease. Throughout the disease, subclinical inflammation persists into the remission period. It is known that chronic inflammation causes endothelial dysfunction and, as a consequence, arterial stiffness occurs. In this study, carotid and aortic intima–media thicknesses (IMT) and arterial stiffness were measured in FMF patients to evaluate the risk of possible vascular damage due to chronic inflammation. Methods: The study included pediatric patients with FMF who had been in remission for a minimum of 3 months. Carotid and aortic IMT and arterial stiffness measurements were conducted using sonoelastography. The acute-phase reactants were also evaluated in all participants. Results: Carotid artery stiffness measurements by strain elastography were significantly higher in the patient group than in the control group. However, the aortic and carotid IMT were similar between the two groups. The acute-phase reactants were significantly higher in the patient group than in the control group. Conclusions: This study demonstrated that arterial stiffness increased in pediatric FMF patients. According to the results of the present study, the effects of chronic inflammation on arterial tissues may lead to atherosclerotic changes in the later stages of the disease and may pose a risk for coronary diseases. Arterial ultrasonographic and elastographic measurements to be performed periodically in children with FMF are noninvasive methods that can be used to evaluate the course of endothelial damage. We aimed to show that arterial stiffness may be a marker of early cardiovascular disease. Full article
(This article belongs to the Special Issue Pediatric Radiologic Imaging: The Current Status and Further Prospects)
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Review

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11 pages, 2941 KiB  
Review
Contrast-Enhanced Ultrasound (CEUS) and Ultra-Microangiography (UMA) in Critically Ill Children with Acute Kidney Injury
by Nace Ogorevc, Peter Slak, Stevan Nikšić, Gregor Novljan, Petja Fister and Domen Plut
Children 2024, 11(10), 1205; https://doi.org/10.3390/children11101205 - 30 Sep 2024
Cited by 1 | Viewed by 1131
Abstract
Acute kidney injury (AKI) is an acute condition of impaired kidney function with decreased glomerular filtration rate, which results in dysregulation in volume, electrolyte, and acid–base equilibrium. AKI can be a life-threatening condition and can also lead to chronic kidney disease. It is [...] Read more.
Acute kidney injury (AKI) is an acute condition of impaired kidney function with decreased glomerular filtration rate, which results in dysregulation in volume, electrolyte, and acid–base equilibrium. AKI can be a life-threatening condition and can also lead to chronic kidney disease. It is important to diagnose AKI early in the course of the disease or to predict its development, as this can influence therapeutic decisions, outcome, and, consequently, the prognosis. In clinical practice, an elevated serum creatinine concentration remains the most common laboratory indicator for diagnosing AKI. However, due to the delay in its rise, creatinine levels are often insensitive and inaccurate for early diagnosis. Novel biomarkers of kidney tubular injury and the renal angina index have shown promise in predicting AKI earlier and more accurately. Contrast-enhanced ultrasonography (CEUS) and ultra-microangiography (UMA) are radiological methods that can quantify renal microperfusion and may be able to predict the development of AKI. They have not yet been used for quantifying renal perfusion in children with risk factors for developing AKI. Further research is needed to compare these sonographic techniques with the renal angina index and emerging kidney injury biomarkers for predicting acute kidney injury (AKI) in both children and adults. Full article
(This article belongs to the Special Issue Pediatric Radiologic Imaging: The Current Status and Further Prospects)
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