Pediatric Solid Tumor: Precision Medicine and Long-Term Prognosis

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Hematology & Oncology".

Deadline for manuscript submissions: 20 February 2026 | Viewed by 4

Special Issue Editors


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Guest Editor
Department of Radiology, Nemours Children’s Health, Wilmington, DE 19803, USA
Interests: tumor targeting; drug delivery; radiochemistry; drug quality control and nuclear medicine; molecular imaging; tissue engineering
Department of Radiology, Diagnostic and Research PET/MR Center, Nemours Children’s Health, Wilmington, DE 19803, USA
Interests: radiochemistry; neuroimaging; organic chemistry; nuclear medicine; molecular imaging
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Special Issue Information

Dear Colleagues,

Pediatric solid tumors represent a complex and heterogeneous set of cancers that demand highly tailored approaches to diagnosis, treatment, and long-term care. Precision medicine offers the potential for personalized therapies guided by molecular profiling, genomic alterations, and tumor biology; however, its adoption in pediatric oncology remains far from universal.

Key obstacles include inconsistent implementation across healthcare systems, a lack of robust evidence in varied patient populations, and persistent inequities in access. Predictive genomic risk models may underperform in underrepresented groups, while the routine use of multi-omics data is hampered by significant analytical and operational challenges. Overcoming these barriers is essential to achieving meaningful gains in survival, quality of life, and long-term health outcomes for all children.

This Special Issue welcomes original research, clinical studies, and reviews addressing the following:

  • Novel diagnostic tools and molecular targets;
  • Strategies for treatment optimization and overcoming resistance;
  • Methods for integrating multi-omics data into clinical decision-making;
  • Long-term monitoring and survivorship care;
  • Health equity, access, and implementation of science approaches;
  • Real-world evaluations of health outcomes.

We look forward to advancing this vital field together.

Dr. Hanieh Karimi
Dr. Xuyi Yue
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric solid tumors
  • precision medicine
  • molecular profiling
  • targeted therapy
  • tumor biomarkers
  • treatment resistance
  • prognosis
  • survivorship
  • diagnostic tools
  • translational research

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Published Papers

This special issue is now open for submission.
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