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Ultrasonography Interventions in Neonatal and Perinatal Medicine

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Dear Colleagues,

We are pleased to invite you to contribute to our Special Issue of MDPI’s Children, entitled Ultrasonography Interventions in Neonatal and Perinatal Medicine.

The use of ultrasonography is widespread in perinatology and neonatology and, due to the proper use of ultrasonography during pregnancy, we can now discover structural defects in the fetus from the first trimester. Detecting such abnormalities contributes to the well-being of the pregnancy and the informed decision of the parents regarding the future of the fetus. With the help of genetic testing, most genetic syndromes are diagnosed correctly from the early stages of fetal development. When the baby is born, in most cases, the neonatologist is already informed about possible developmental issues encountered during pregnancy and, therefore, the medical team is ready to face the challenges of complicated pathologies.

In neonatology, ultrasonography is used daily and has applications from the delivery room to the NICU and ambulatory daycare. In recent years, POCUS has gained momentum and is now frequently used and helps neonatologists and pediatricians identify the correct treatment for infants. Handheld ultrasound devices are now used often and with ease and deliver improved results even when used by beginners in the field of ultrasonography.

We are certain that together we will provide valuable medical articles to doctors around the world and will improve the everyday practice of ultrasonography.

Dr. Vlad Dima
Prof. Dr. Claudia Mehedintu
Dr. Roxana Elena Bohiltea
Guest Editors

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Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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16 pages, 3382 KiB

Open AccessArticle

Cerebral Ultrasound at Term-Equivalent Age: Correlations with Neuro-Motor Outcomes at 12–24 Months Corrected Age

by Adrian Ioan Toma, Vlad Dima, Lidia Rusu, Alexandra Floriana Nemeș, Bogdan Florin Gonț, Alexandra Arghirescu, Andreea Necula, Alina Fieraru, Roxana Stoiciu, Larisa Andrășoaie, Loredana Mitran, Claudia Mehedințu and Al Jashi Isam

Children 2025, 12(1), 30; https://doi.org/10.3390/children12010030 - 28 Dec 2024

Cited by 1 | Viewed by 666

Abstract

Background/Objectives: Our research aimed to assess if correlations could be found between items evaluated at the cerebral ultrasound performed at term-equivalent age (TEA) and neuro-motor outcomes evaluated at 12 and 24 months of corrected age in a group of preterm infants. Methods: The following were assessed: the Levine Index, the diagonals of the lateral ventricles, the size of the ventricular midbody, the sinocortical distance, the width of the basal ganglia, the cortical depth at the level of the cingular sulcus and the maturation of the gyral folding. The neurologic evaluation was performed at 12 and 24 months of corrected age, according to the Amiel Tison neurologic examination, and the items from the calendar of motor acquisitions were used as outcome measures of the study—gross and fine motor subsets. The comparisons between the different groups were performed using the FANOVA test, with a statistically significant association for a p < 0.05. Results: The abnormal gross motor acquisitions at 12 months were significantly associated with an increased size of the ventricular midbody (p < 0.009) and a significantly decreased diameter of the basal ganglia (p < 0.011) on the TEA cerebral ultrasound. At 24 months, a significant association was found with increased size of the ventricular midbody (>10.33 mm) (p < 0.001), a decreased diameter of the basal ganglia (<12.9 mm) (p < 0.016), a decreased cortical depth (p < 0.021) and an immature gyral maturation pattern (p < 0.001). In the case of severely abnormal fine motor outcomes, at 12 months, there were statistically significant associations with an increased size of the ventricular midbody (p < 0.001) and an immature gyral folding pattern (p < 0.0180); at 24 months, significant associations were noted with the size of ventricular midbody (p < 0.001), a decreased diameter of the basal ganglia (p < 0.016), a decreased cortical depth (p < 0.021) and an immature gyration folding (p < 0.001). Conclusions: The abnormal gross and fine motor outcome in former premature infants at 12–24 months corrected age is significantly associated with abnormal findings in the head ultrasound examination performed at TEA reflecting both white matter (increased midbody distance) and grey matter (decreased diameter of the basal ganglia, decreased cortical depth and an immature gyration pattern) involvement. Full article

(This article belongs to the Special Issue Ultrasonography Interventions in Neonatal and Perinatal Medicine)

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