Pediatric Palliative Care and Pain Management

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Anesthesiology, Pain Medicine and Palliative Care".

Deadline for manuscript submissions: 1 November 2025 | Viewed by 94

Special Issue Editor


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Guest Editor
1. Divisions of Neonatology and Pain & Palliative Care, UConn School of Medicine, Farmington, CT 06032, USA
2. Connecticut Children’s Medical Center, Hartford, CT 06106, USA
Interests: improving outcomes for neonates with complex diagnoses; complex fetal diagnoses and in utero therapies; neonatal/perinatal palliative care; neonatal pain management; bereaved parent experiences; communication in counseling and shared decision-making

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to this Special Issue, ‘Pediatric Palliative Care and Pain Management'. Palliative care is a total approach to care that aims to improve the quality of life of patients who are facing a complex serious illness or potentially life-limiting diagnosis. Our focus is on preventing and relieving suffering through the early identification, assessment, and treatment of pain and other problems, whether physical, psychosocial, or spiritual, for the patient and their entire family. While pediatric palliative care evolved out of the field of hospice and palliative medicine, it requires a different approach to children than in adults. For each family, care is unique and is continued irrespective of the disease trajectory, treatment options chosen, or transitions in care settings. In 2000, the American Academy of Pediatrics issued its first policy statement on pediatric palliative and end-of-life care, calling for “the development of clinical policies and minimum standards that promote the welfare of infants and children living with life-threatening or terminal conditions and their families, with the goal of providing equitable and effective support for curative, life-prolonging, and palliative care”. With innovative therapies, more critically ill and medically complex patients are surviving. These neonates and children are exposed to more invasive procedures that may cause pain and may experience various forms of pain as a result of their underlying diagnosis. With this increased acceptance and understanding of the impact of untreated pain, stress, and agitation in neonates and children, multiple medical societies, including the American Academy of Pediatrics and the Society of Critical Care Medicine, have endorsed the importance of treating sedation, analgesia, and delirium, as well as the importance of intentional practices.

While there remains a paucity of data, research has highlighted the importance of pediatric palliative care, gaps in care, experiences of patients and families, and different structures to provide this care.

This Special Issue aims to highlight important topics related to pediatric palliative care, neonatal-perinatal palliative care, and pediatric and neonatal pain and advanced symptom management. Topics may include (but are not limited to) the following: program development (including multi-specialty/discipline collaborations); quality improvement measures in pediatric palliative care and pediatric pain management; education, training, and curriculum development in pediatric palliative care and pain management; collaborations, outcomes, and care of medically complex neonates and children (cardiology, neurology, nephrology, etc.); ethical aspects of pediatric palliative care in various countries; advanced pain and symptom management (delirium, complex sedation and analgesia, wound care, etc.); disparities in pediatric palliative care; cultural and religious dimensions of neonatal-perinatal palliative care; the short- and long-term impact of pain and stress on the developing brain; and the long-term impact of medications to treat pain and other symptoms on the developing brain.

We look forward to receiving your contributions.

Dr. DonnaMaria E. Cortezzo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric palliative care
  • neonatal palliative care
  • perinatal palliative care
  • pain management
  • end-of-life care
  • end-of-life symptom management
  • chronic pain
  • pediatric pain
  • neonatal pain
  • impact of pain and pain management on neurodevelopment

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Published Papers (1 paper)

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12 pages, 1329 KiB  
Brief Report
Rapid, Safe, and Tolerable Healing of Pediatric Skin Injuries with Blue Light Therapy: An Observational Case Series
by Nicolosi Biagio, Bastarelli Eleonora, Gregorini Mirco and Ciprandi Guido
Children 2025, 12(6), 801; https://doi.org/10.3390/children12060801 - 19 Jun 2025
Abstract
Background/Objectives: Pediatric skin injuries represent a clinical challenge, especially in cases with complex etiology or with severe pain. Blue light is an emerging technology with potential application in pediatric wound care. The aim of this case series was to describe the clinical use [...] Read more.
Background/Objectives: Pediatric skin injuries represent a clinical challenge, especially in cases with complex etiology or with severe pain. Blue light is an emerging technology with potential application in pediatric wound care. The aim of this case series was to describe the clinical use of blue light in pediatric patients with injuries of varying etiologies and mechanisms, and to assess its long-term effectiveness and sustainability in treatment. Methods: Twelve hospitalized pediatric patients (0–12 years old) with skin injuries were included in this case series. The etiologies of wounds treated with photobiomodulation were incontinence-associated dermatitis, peristomal injuries, and pressure injuries. The injuries were assessed using specific classification tools and pain scales. The wounds were treated every three days using a medical device that emits blue light (410–430 nm). When necessary, wounds were also treated with appropriate dressings. Results: All injuries responded positively to photobiomodulation therapy and showed a rapid resolution of inflammation. Complete wound resolution was achieved in 11 of 12 cases. The average healing time was 3.7 days. Four injuries achieved resolution with only one application of blue light. Scores from the pain perception scales showed that the blue light treatment was well tolerated by pediatric patients, showing high parental compliance. No side effects or adverse events were observed. Conclusions: Blue light photobiomodulation proved to be a safe, well-tolerated, and effective technology in the treatment of pediatric skin injuries, with good acceptance by young patients and families. More structured clinical trials would be needed to validate the efficacy of blue light in pediatric injuries. Full article
(This article belongs to the Special Issue Pediatric Palliative Care and Pain Management)
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