Single Cell Omics: Recent Advances and Application in Cellular Pathology

Dear Colleagues,

Recent advances in next-generation sequencing technologies have led to an explosion in multi-omics datasets (e.g., genomics, transcriptomics, epigenomics, metabolomics, proteomics, microbiomics, etc.), which has been accompanied by the development of novel computational genomics tools to analyze these data and perform integrative analysis. Together, these approaches have rapidly expanded the number of discoveries for complex cell and tissue development, and diseases such as cardiovascular development and disease, neurological development and diseases, cancer, immune interactions and diseases, etc.

Advances in single-cell approaches are now enabling us to study differences between cell types and subpopulations, at the level of the genome, transcriptome, epigenome, proteomics, etc. Single-cell technologies are being used to study diverse areas of biology and disease, such as cardiovascular and neurological development, microbial population composition, and cancer evolution.

In this Special Issue, we hope to bring together experts in multi-omics from multi-disciplinary backgrounds, including experimental methodology, computational data analysis, and biomedical applications to share their collective expertise in a broad range of topics related to single-cell omics data integration for various complex diseases. The Cells journal highlights the emergence of this field with a Special Issue focused on single-cell methods, data analysis, and their applications. We welcome multiple manuscript formats, including original research articles, reviews or mini-reviews, opinions, hypotheses, or reports.

Dr. Huaxiao Adam Yang
Dr. Mingtao Zhao
Dr. Qiwei Li
Dr. Lin Xu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• single cell omics
• complex diseases
• computational systems biology
• cellular pathology
• developmental biology