Decoding Cancer Transcriptome Non-Coding RNAs and Beyond

Dear Colleagues,

The discovery of non-coding RNAs has revitalized the biology field, from the basic to translational research spectrum. Non-coding RNAs (ncRNAs) are functional molecules that are not translated into proteins and comprise almost the 80% of mammalian transcriptome. They have been categorized into different classes, mostly depending on their genomic location, cellular localization, and their size.

NcRNAs are master regulators of gene expression at the transcriptional and/or post-transcriptional level and play fundamental roles in development, tissue/cellular homeostasis, and human pathophysiology. It is now established that ncRNAs work in concert with other epigenetic mechanisms, including DNA methylation and histone modifications, to control gene expression and regulate cancer initiation, growth, and metastasis. Given their cell- and tissue-specific expression patterns, many ncRNAs have emerged as a potential biomarker and therapeutic tool in many types of cancer.

This issue focuses on cutting-edge research across different types of ncRNAs, relevant to cancer and cancer inflammation. We invite authors to submit original, meta-analyses and review articles on basic research, translational and cancer diagnosis or treatment.   

Dr. Maria Hatziapostolou
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.