Extracellular Vesicles as Regulators of Inflammatory Diseases

Dear Colleagues,

Inflammation, the defense mechanism of the immune system against harmful stimuli, like pathogens, is characterized by tissue redness, swelling, heat, pain, and loss of functions. Inflammation aids in the recruitment of immune cells at the infection site, which not only eliminates the pathogens, but also triggers the healing process. However, prolonged inflammation often promotes various chronic inflammatory diseases; therefore, a balance between pro- and anti-inflammatory responses is essential in eliminating the pathogens with limited damage to the host. Extracellular vesicles (EVs) are nanosized membranous structures which allow cell–cell communication via the transfer of bioactive molecules, such as proteins, lipids, nucleic acids, etc. Emerging evidence indicates that EVs play a major role in various inflammatory diseases.

The Special Issue aims to delineate the role of EVs in the pathogenesis of several inflammatory diseases, their use as disease biomarkers, and implications in targeted therapy against several inflammation-associated diseases.

Dr. Kaushik Das
Guest Editor

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