Ischemic Heart Disease: From Cellular Level to Clinical Approaches
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 25 March 2026 | Viewed by 680
Special Issue Editors
Interests: ischaemic heart disease; PCI; chronic total occlusion
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute to this upcoming Special Issue, entitled “Ischemic Heart Disease: From Cellular Level to Clinical Approaches.”
Ischemic heart disease (IHD) remains a leading cause of morbidity and mortality worldwide, with a complex pathophysiology rooted in molecular and cellular dysfunction. This Special Issue will highlight cutting-edge research that explores the fundamental mechanisms underlying IHD and its clinical manifestations—from classic myocardial ischemia and reperfusion injury to inflammation, chronic remodeling, and fibrosis.
We particularly welcome studies focusing on oxidative stress, mitochondrial dysfunction, inflammatory signaling, endothelial biology, and cardiomyocyte death pathways. Emerging areas such as epigenetic regulation, non-coding RNAs, immunometabolism, and single-cell transcriptomics are of particular interest, as they offer new therapeutic insights and precision medicine opportunities.
Additionally, we encourage contributions exploring mechanisms of angiogenesis, ischemic preconditioning, and advanced nanotechnology-based drug delivery systems. Both original research articles and reviews are welcome, provided that they offer strong molecular or cellular insights relevant to the pathogenesis, diagnosis, or treatment of ischemic heart disease.
By integrating diverse experimental approaches, this Special Issue will deepen our understanding of IHD and accelerate the development of targeted interventions.
We look forward to receiving your valuable contributions.
Dr. Stefan A. Juričić
Dr. Milan R. Dobrić
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- ischemic heart disease
- myocardial ischemia
- reperfusion injury
- oxidative stress
- mitochondrial dysfunction
- cardiomyocyte death
- endothelial dysfunction
- inflammation
- fibrosis
- epigenetics
- non-coding RNAs
- immunometabolism
- single-cell transcriptomics
- angiogenesis
- ischemic preconditioning
- nanomedicine
- molecular cardiology
- targeted therapy
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