Special Issue "Photodynamic Biology"
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 344
Interests: calcium oscillations; exocytosis; photodynamic therapy
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Photodynamic action, as originally defined, is oxygen-dependent action. Delta singlet oxygen (D1O2) is an extensively studied type II photodynamic action involving excited state molecular oxygen, and it is responsible for modulating numerous cellular functions, including cell secretion, muscle contraction, cellular signaling, cell death and senescence, autophagy, gene transcription and translation, development, and protein oxidation. Although photodynamic action has been extensively studied in the context of diagnosis and therapy in addition to as a research tool for teasing apart specific cellular and molecular details, studies aiming to define the mechanisms of action at the cellular and molecular levels are scattered in the literature, in large numbers of journals and covering multiple disciplines. This Special Issue aims to call for a series of clearly defined cases of photodynamic modulation of biological activities, for example, modulation of all categories of functional proteins as defined by the International Union of Basic and Clinical Pharmacology (https://bpspubs.onlinelibrary.wiley.com/toc/14765381/2021/178/S1): (1) G protein coupled receptors; (2) ionic channels; (3) transporters; (4) enzymes; (5) catalytic receptors; (6) nuclear hormone receptors; (7) other functional proteins.
The biological or enzyme-catalyzed generation, reaction, and quenching of delta singlet oxygen is of physiological and biochemical significance also of particular interest to this Special Issue. The focus of the contribution could also be on the light source (bioluminescence, for example) driving the photodynamic action photosensitizers (genetically encoded protein photosensitizers, for example) and their tagging patterns to the target of interest (TOI).
It is the hope of this Special Issue, jointly hosted by Biomedicines and Cells, to advance the field in a significant way and identify areas for future investigations in the next decade and beyond.
Contributions in the form of original articles or reviews focused on pivotal topics in the field of photodynamic biology are welcome.
Dr. Zong Jie Cui
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- photodynamic action
- singlet oxygen
- cellular function
- functional proteins
- bioluminescent proteins as light sources