Hepatitis Virus Infection Tropism, Transmission, Pathogenesis and the Host Response
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (15 July 2023) | Viewed by 299
Special Issue Editors
Interests: hepatitis viruses (HAV, HBV, HCV, HDV, and HEV) infection species tropisim and the restriction factors; animal models for hepatits virus in vivo research; oncogenesis of hepatitis virus infection; non-coding RNAs; CRISPR-based genome editing and modification
Interests: laboratory diagnosis of viral hepatitis; mechanism of interaction between HBV and host; translational study of HBV infection-related HCC
Special Issue Information
Dear Colleagues,
As we all know, millions of people worldwide are infected with human hepatotropic pathogens, hepatitis viruses including hepatitis A–E viruses, which pose serious public health concerns including viral hepatitis, liver fibrosis, or even, liver cancer after long-time chronic infection. Hepatitis A and B are vaccine-preventable liver infections, while mother-to-child vertical transmission and a large amount of already existing infections for HBV are still big issues. HEV is the major leading cause of enterically transmitted viral hepatitis and there are an estimated 20 million HEV infections worldwide every year. Additionally, HEV can cause up to 30% mortality in pregnant women and can become chronic in immunocompromised individuals. HBV (and its satellite virus HDV) and HCV exhibit nearly unique human tropism, posing additional challenges for studying host–pathogen interactions and for efficiently testing antimicrobial intervention strategies.
This Special Issue aims to publish a broad range of articles covering topics including (but not limited to) virology, animal models, infection models, viral–host interactions, immune responses, pathogenesis, and antivirals related to hepatitis viruses. Therapeutic or preventive vaccines and novel biotechnology developed/applied for hepatitis virus research are also welcome. Research articles, short communications, and reviews are welcome. All papers will be published on an ongoing basis with full open access. The topics of interest include but are not limited to the following:
- Hepatitis virus (HAV, HBV, HCV, HDV, HEV) virology;
- Viral hepatitis epidemiology;
- Viral infection-related liver diseases;
- Animal models for hepatitis virus infection;
- HBV transgenic mice;
- Antiviral drug development for hepatitis viruses;
- Viral–host interactions;
- HBV mother-to-child vertical transmission.
We believe the papers in this Special Issue will provide the readers with state-of-the-art research findings and progress in the field of hepatitis viruses, and they will shed light on new possible strategies to control and treat hepatitis virus-associated liver diseases. We look forward to receiving your interesting contributions and believe your research will be widely spread and recognized from this Special Issue.
Dr. Yongzhen Liu
Dr. Xiangmei Chen
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- hepatitis viruses
- infection tropism
- animal model
- liver disease
- oncogenesis
- virus–host interaction
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