Special Issue "Mechanisms of Ischemic Heart Injury"
Deadline for manuscript submissions: closed (10 December 2021) | Viewed by 6435
Cardiovascular disease remains a leading cause of morbidity and mortality worldwide, as well as an enormous global economic burden. Myocardial infarction, primarily the result of coronary artery disease, elicits massive cardiomyocyte loss and irreparable damage to heart muscle, leading to impaired cardiac function and heart failure. The current standard of care to treat patients suffering myocardial infarction—typically primary percutaneous coronary intervention to allow myocardial reperfusion—limits the loss of viable myocardium. Paradoxically however, timely intervention does not prevent the additional tissue damage resulting from the act of reperfusion itself, which may contribute to injury and worsen outcomes. An incomplete understanding of the mechanisms underlying myocardial ischemia and reperfusion injury remains a significant barrier to improved therapeutics to mitigate cardiac damage.
This Special Issue aims to summarize the current knowledge related to ischemic heart injury, and to enhance our understanding of basic mechanisms underlying this phenomenon, with the hope of advancing the field toward novel potential therapeutic strategies to improve patient outcomes.
We look forward to your contribution to this Special Issue of Cells.
Prof. Dominic P. Del Re
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- heart failure
- myocardial infarction
- cell death