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Functional Role of microRNAs in Regulating Cardiomyocyte Death

1
Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Einstein Institute for Aging Research, Institute for Neuroimmunology and Inflammation (INI), Albert Einstein College of Medicine, New York, NY 10461, USA
2
Department of Molecular Pharmacology, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), Fleischer Institute for Diabetes and Metabolism (FIDAM), Albert Einstein College of Medicine, New York, NY 10461, USA
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Dominic P. Del Re
Cells 2022, 11(6), 983; https://doi.org/10.3390/cells11060983
Received: 10 December 2021 / Revised: 8 March 2022 / Accepted: 9 March 2022 / Published: 12 March 2022
(This article belongs to the Special Issue Mechanisms of Ischemic Heart Injury)
microRNAs (miRNA, miRs) play crucial roles in cardiovascular disease regulating numerous processes, including inflammation, cell proliferation, angiogenesis, and cell death. Herein, we present an updated and comprehensive overview of the functional involvement of miRs in the regulation of cardiomyocyte death, a central event in acute myocardial infarction, ischemia/reperfusion, and heart failure. Specifically, in this systematic review we are focusing on necrosis, apoptosis, and autophagy. View Full-Text
Keywords: cell death; cardiomyocytes; ischemia/reperfusion; myocardial infarction; heart failure; autophagy; apoptosis; necrosis; non-coding RNA cell death; cardiomyocytes; ischemia/reperfusion; myocardial infarction; heart failure; autophagy; apoptosis; necrosis; non-coding RNA
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MDPI and ACS Style

Kansakar, U.; Varzideh, F.; Mone, P.; Jankauskas, S.S.; Santulli, G. Functional Role of microRNAs in Regulating Cardiomyocyte Death. Cells 2022, 11, 983. https://doi.org/10.3390/cells11060983

AMA Style

Kansakar U, Varzideh F, Mone P, Jankauskas SS, Santulli G. Functional Role of microRNAs in Regulating Cardiomyocyte Death. Cells. 2022; 11(6):983. https://doi.org/10.3390/cells11060983

Chicago/Turabian Style

Kansakar, Urna, Fahimeh Varzideh, Pasquale Mone, Stanislovas S. Jankauskas, and Gaetano Santulli. 2022. "Functional Role of microRNAs in Regulating Cardiomyocyte Death" Cells 11, no. 6: 983. https://doi.org/10.3390/cells11060983

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