Exploring the Cellular Basis of Steatotic Liver Disease: Insights and Advances
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (31 May 2025) | Viewed by 705
Special Issue Editor
Interests: metabolic dysfunction-associated steatotic liver disease (MASLD); inflammatory liver disease; biomarkers; liver fibrosis; macrophages
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as a leading cause of chronic liver disease worldwide, with its progression ranging from simple steatosis to more severe conditions such as metabolic dysfunction-associated steatohepatitis (MASH), fibrosis, and cirrhosis. Despite its prevalence, the cellular mechanisms underlying MASLD and its progression are still not fully understood. This Special Issue of Cells aims to explore recent insights into the cellular basis of fatty liver disease, shedding light on the complex interplay between hepatocytes, hepatic stellate cells, Kupffer cells, and immune cells in the context of lipid metabolism, inflammation, and fibrosis. Furthermore, this Special Issue will highlight advanced in vitro and in vivo models and discuss novel biomarkers and potential therapeutic strategies targeting cellular pathways to mitigate disease progression.
We invite contributions that cover cellular signaling, lipid metabolism, mitochondrial dysfunction, oxidative stress, and the role of the gut–liver axis, offering new perspectives on both the pathogenesis and potential therapeutic avenues for NAFLD.
Yours faithfully,
The Guest Editor
Prof. Dr. Henning Gronbaek
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolic dysfunction-associated steatotic liver disease (MASLD)
- hepatocytes
- hepatic stellate cells
- lipid metabolism
- inflammation
- fibrosis
- mitochondrial dysfunction
- Kupffer cells
- the microbiome
- the gut–liver axis
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
