Epigenetic Mechanisms of Tumorigenesis
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 10 September 2025 | Viewed by 763
Special Issue Editor
Interests: histone H2A deubiquitinase; tumorigenesis; ubiquitination; epigenetic mechanisms
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Tumorigenesis, the complex process by which normal cells transform into cancerous ones, is influenced by genetic mutations and epigenetic alterations. Epigenetic mechanisms, including DNA methylation, histone modifications, and non-coding RNA interactions, have a critical role in regulating gene expression without altering the underlying DNA sequence. These mechanisms are pivotal in maintaining cellular identity and function, but when disrupted, they can lead to aberrant gene expression profiles, contributing to cancer initiation and progression.
This Special Issue delves into the diverse epigenetic landscapes that drive tumorigenesis, exploring the latest research on how these modifications contribute to the onset and progression of various cancers. By understanding these processes, we can uncover novel biomarkers for early detection and therapeutic targets to develop more precise and effective cancer treatments. This compilation of studies and reviews provides a comprehensive overview of the current state of epigenetic research in oncology, highlighting both the challenges and opportunities in this rapidly evolving field.
Prof. Dr. Hengbin Wang
Guest Editor
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Keywords
- epigenetics
- tumorigenesis
- gene expression
- cell identity
- precise medicine
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